It can be hard to admit that one drug that you have been giving to a lot of patients may not be doing much of anything at all.
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In fact, at the prices that would have to be charged, there would not be much of an auto industry.
Also it is readily acknowledged that, in part as a result of these unscripted developments, Moscow may not be in much of a position at the moment fully to exploit the opportunities available to it.
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To put it another way, governments set up a system that in effect treated bankers as naughty children or ravenous puppies who could not be trusted not to eat too much of the dangerously fattening stuff - and regulators were to be the health conscious parents.
But it may not be as much of a no-brainer for smartphones, says Forrester security analyst Andrew Jaquith.
Without the DAP there would not be much of an opposition in Malaysia.
If the bond markets dry up, there will not be much prospect of emerging economies financing themselves in other ways.
But by the time any error is reversed, there might not be much of WorldCom left to compensate his clients.
Adult males have very hollow abdomens and will not be much of a mouthful, but the females are filled with fat.
Once again, national opinion polls may not be much of a guide.
For example, a GED might not be of much value for workers already near retirement age, and many GED programs have long waiting lists.
But if the parties put together a sweeping alliance, the resulting parliament may not be much of a forum for Iraqis to air their grievances.
So the US taxpayers will not be receiving much of a return on their investment due to failure to pay the costs of maintaining their investment.
But he thinks Abbas and Israeli Prime Minister Ehud Olmert are still too far apart, and Rice's style of letting the parties take the lead may not be of much help.
The public queued for seats at the hearing but but many left after about half an hour when it became clear that this would not be much of a show.
That might not be too much of a stretch.
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Alpha has always been a slippery concept: in theory there should not be much of it about and academics have struggled to find evidence that the industry consistently realises it for clients.
But while the bills, designed to make universities disclose their process for choosing preferred lenders, are expected to pass, experts say there will probably not be much of an impact on the industry.
Novelty bathroom tissue may not be much of a perk, but some of the other fringe benefits Armstrong and his new content chief, Arianna Huffington, have introduced of late have more appeal.
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Holding on to a slightly slower iPhone might not be much of an issue if you primarily use it for common tasks -- calls and texts, e-mailing, Twitter and Facebook, reading, even watching movies.
But it would not be much of one.
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This would reassure investors that waiting for the market to reach a "bottom" will not be of much benefit, because the home values of these modified mortgages will be guaranteed at the price level when modified.
Price may not be much of a deterrent for the market Zero is targeting, but for those who might consider one of its bikes prohibitively expensive, a New York-based company, Evolve Motorcycles, will soon offer plug-in motorcycles and scooters as well.
In the past we talked about "dual use" military-civilian technologies, but truth be told, not much of what's in a bomb migrates back to a BMW. However, the money flowing into military and homeland infra-structure security will leverage revolutionary technologies and materials of the new digital age.
Amid bitterly cold conditions and heavy snowfall, the players deserved credit for the general quality of the first half - but the same could not be said about much of the second.
"Kevin will be missed but he will not be missed too much because of the way he has been playing as the injury has been affecting him so much, " said Vaughan.
The trouble is, the Bank of England's policy of raising interest rates seems to be hurting manufacturers but not putting much of a squeeze on sellers of services, the true villains of the piece.
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