Some town centre roads will be closed to traffic, including Midsummer Boulevard, Saxon Gate and Grafton Gate.
BBC: Milton Keynes Red Bull celebration set to attract crowds
The road will be closed to traffic between Bullbridge Hill and New Road.
Queensway Mersey Tunnel will be closed to traffic in both directions until 06:30 BST on Tuesday to accommodate the festival.
In fact, Vanderbilt would be closed to traffic to make way for a plaza as soon as funds are available.
More than 4, 000 agents will be deployed, gunboats will patrol the Bosporus, and many streets will be closed to traffic.
The ceremony is traditionally held on a Sunday, when the city's streets can be closed to traffic near the Vatican.
In Gloucestershire, police warned motorists to avoid the flood-hit village of Lower Lydbrook where the main road had to be closed to traffic.
The remainder of the A-road will be closed to traffic in late 2013, to allow a shuttle to operate between the visitor centre and the stones.
While the bridge will not be closed completely to traffic, Transport Scotland hope commuters will make greater use of public transport to help minimise congestion.
The city council said London Road would be closed to A6 traffic between Bateman St and the Rail Technical Centre, from September 2013 until August 2014.
BBC: A6: Derby's London Road Bridge to close for up to a year
People will likely opt for the Metro, because two of the major routes coming into the city, I-395 and I-66, will be closed to inbound traffic for private vehicles.
CNN: Washington locals excited, but bracing for inconvenience
Motorists are being warned that the Queensway Mersey Tunnel will be closed to all traffic in both directions from 2200 BST on Saturday until 0630 BST on Tuesday to accommodate the festival.
For five hours this Sunday, some 10 miles of normally car-crowded Los Angeles streets will be closed to vehicular traffic and turned into a massive block party for cyclists, pedestrians, joggers, even stilt-walkers.
Additionally, air-traffic control towers at 149 smaller airports nationwide are slated to be closed starting April 7.
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