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Genasense blocks a gene called BCL-2, which produces a protein that prevents cells from self-destructing through a process called apoptosis.
FORBES: Genta's Tangled Path
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Chemotherapy works by traumatizing cancer cells until they kill themselves, and getting rid of BCL-2 makes it easier to eliminate the cancerous cells.
FORBES: Genta's Tangled Path
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Genasense, which is used in combination with chemotherapy, works by targeting a key "cell suicide" gene called bcl-2 and then inducing cancer cells to kill themselves.
FORBES: Magazine Article
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Examination of 75 patients showed that the activity of bcl-2 in a tumour was a strong indicator that a patient would respond well to a drug called tamoxifen.
ECONOMIST: An un-killer app
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"I don't think that either the people who discovered BCL-2 in the late '80s or the people at Genta back in 1992 knew what they were picking up, " says Warrell.
FORBES: Genta's Tangled Path
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The BCL-15 f8.0 Body Cap Lens serves as a body cap when carrying the camera around without its interchangeable lens, and transforms to become a pan-focus snapshot lens to capture images.
ENGADGET: Olympus E-PL5 and E-PM2: Micro Four Thirds cameras with OM-D-like focusing, performance boosts (hands-on)
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Dr Meterissian presented the results of a study showing how two genes, called bcl-2 and p53, could be used to predict the responses to different treatments of patients with breast cancer.
ECONOMIST: An un-killer app