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Early this week, the last straw was a bad call by a replacement referee that gave the win to the Green Bay Packers over the Seattle Seahawks.
FORBES: 4 Mistakes The NFL Made In The Lockout Negotiations
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Changes in the population of bacteria, such as removal of some of the good bacteria or replacement with some bad bacteria, can lead to a variety of health problems, especially inflammation of the bowel, diarrhea and pain.
CNN: Could I become dependent on probiotics?
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Things went from bad to worse for Tonga as replacement Toma Toke was shown a yellow card for a high tackle to reduce the Sea Eagles to 13 men.
BBC: Samoa 15-19 Tonga
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The drug company piles more bad news on top of its hormone replacement disaster.
FORBES: The Heavy Weight Of Clinical Trials
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Monty bristled when I made a bad joke about Ford becoming a car-rental replacement for bloggers.
FORBES: So, Why Would Ford Loan Someone Like Me a Car?
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LakerFail has been a media-saturating saga for months, starting with the firing of coach Mike Brown in early November through the struggles of replacement coach Mike D'Antoni to the recent weeks of intrasquad bad feelings among the team's biggest names.
WSJ: Los Angeles Lakers: The Loopy Mess of LakerFail
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The bad news is that Capellas' first order of business, if he is in fact Sidgmore's replacement, will be to restore the company's reputation with customers, investors and creditors.
FORBES: Michael Capellas' Next Move
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It was a bad day all round for West Ham's forward line as Carlos Tevez went off injured early on and his replacement Zamora was extremely unfortunate to be sent off on 76 minutes after a sliding challenge.
BBC: Benayoun was in inspired form for West Ham