Lilly and Sankyo have high hopes for the drug, and are testing in a big trial to prove that prasugrel is better that Plavix in preventing heart attacks, strokes and other cardiovascular events in patients at high risk.

FORBES: Plavix Pain

The companies didn't start a big trial testing whether adding Zetia to Zocor prevents heart attacks and strokes until three years after the drug was approved for sale.

FORBES: How Low Can Vytorin Go?

In a bold move, Pfizer is testing Celebrex in patients at high risk for heart attacks--and it says it expects the drug may actually reduce cardiovascular disease.

FORBES: Pfizer Says FDA Warning Likely For Bextra

It turned out the medicine caused heart attacks and deaths, something Pfizer might have prevented by switching to backup molecules it was already testing.

FORBES: In Denial

Another NIH study testing Celebrex as a cancer preventative had found that the drug increased the risk of heart attacks, and patients were dropping out of the Alzheimer's study in droves.

FORBES: Fear Mongering At The FDA

Despite falling behind so early, Shakhtar gave a good account of themselves in the opening stages, with Willian's pace down the left testing Alves and Luiz Adriano posing a constant problem as the focal point of the visitors' attacks.

BBC: Barcelona 5-1 Shakhtar Donetsk