Tell-tale signs of underlying medical problems include significant changes in energy, weight, appetite or sleep, which could be due to an endocrine disorder.

WSJ: Confusing Medical Ailments With Mental Illness

He has spent more than two months in bed under the care of his autocratic wife, Rahsan, and his afflictions range from a spinal disorder via cracked ribs and a thrombosis to loss of appetite.

ECONOMIST: A government on the brink | The

Newer versions (including one of the active ingredients in Adderall) were introduced as appetite suppressants in the 1950s and were soon being used to treat ADHD, then a rarely diagnosed disorder that made it hard for kids to function in school.

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