Clarinex, the company's very similar follow-up antihistamine, may be hurt by all those cut-rate generics.
For allergy season, all she needs is the saline rinse and an oral antihistamine, she said.
An antihistamine such as Benadryl will be given and, in severe cases, a shot of epinephrine.
While a professor at Georgetown University, he studied the antihistamine Seldane, which had been found to cause health problems.
The drug was first marketed in the 1980s as an antihistamine in Russia.
When pollen counts are at their highest, people who have received the injections may still need some antihistamine medications.
Over-the-counter versions could hurt not only Schering-Plough, but other antihistamine makers as well.
And they threaten its ability to maintain the Claritin antihistamine franchise, which accounted for one-third of Schering's revenues last year.
Dimebon, a Russian antihistamine being developed by San Francisco-based Medivation in partnership with Pfizer, has shocked scientists with its apparent efficacy.
That left Aventis as a pure-play drugmaker whose products include Allegra, a blockbuster antihistamine, and Lantus, a long-acting form of insulin.
Those who have had allergic reactions to insects should always carry an antihistamine and an epinephrine auto-injector for emergencies, experts said.
Dissolving it in cremafor, another emulsion, required patients to take an antihistamine beforehand to prevent itching and steroids to avoid breathing problems.
Regardless, Schering-Plough has begun an advertising push to try to convert Claritin users to a new antihistamine, Clarinex, a follow-up to Claritin.
No one could fully explain how an antihistamine might slow the progression of Alzheimer's, although clinical trials conducted in Russia suggested it could.
WSJ: Medivation, Pfizer Alzheimer's Drug Fails to Meet Study Goals
For all the names, the main ingredients are the same: Vitamin B6 plus the over-the-counter antihistamine doxylamine, found in the sleep aid Unisom.
Schering-Plough 's (nyse: SGP - news - people ) Clarinex is a slightly altered form of Claritin, the blockbuster antihistamine.
In particular, Meltzer says, a leukotriene inhibitor like Singulair could be far better at treating nasal congestion than an antihistamine like Claritin or Zyrtec.
As a first stab Rabinowitz picked the antihistamine Benadryl and set about figuring out how to turn this powder into pure, medicinally potent smoke.
This work led to Allegra, an antihistamine that is a blockbuster for Strasbourg, France-based Aventis (nyse: AVE - news - people ).
His next step is the B6-and-antihistamine combination that will form Diclegis.
Many of us have already spent springs feeling like a total wreck, between the sneezing, itchy eyes and sinus headaches, no matter which antihistamine we take.
This drug, an antihistamine used in Russia, emerged from nowhere a couple years ago when Medivation reported that the drug slowed Alzheimer's progression in a big trial in Russia.
Claritin, the non-sedating antihistamine from Schering-Plough (nyse: SGP - news - people ), is often credited with starting off the direct-to-consumer marketing craze in the pharmaceutical industry.
As precedent he cites the example of Seldane, an antihistamine developed by Hoechst Marion Roussel (now Aventis (nyse: AVE - news - people )) to treat hay fever.
Back in February, regulators at the Food and Drug Administration said they wouldn't give Schering the go-ahead to market the antihistamine until it cleared up manufacturing problems with some of its plants.
It took the better part of a decade for dangerous heart side effects to show up in Seldane, an antihistamine made by the company that became Aventis (nyse: AVE - news - people ).
For instance, Raymond Woosley , vice president of health research at the University of Arizona and a noted pharmacologist, has said that the antihistamine Chlor-Trimetron was originally approved not based on a clinical trial, but by a survey of doctors.
The feds claimed the maker of Claritin, in a price war with the producer of the competing drug Allegra, gave concealed discounts to Cigna and PacifiCare Health Systems in the form of "data processing fees, " interest-free loans and "risk share" rebates tied to growth in an insurer's outlays for antihistamine-like drugs.
应用推荐