Ms. Clark belongs to an angel network in Columbus called Ohio TechAngels, which has 282 members.
At the same time, the entrepreneur feels less isolated thanks to expert advice provided by the angel network.
Examples of these groups include Investors' Circle in San Francisco, Hyde Park Angel Network in Chicago and Golden Seeds in New York.
She has co-founded several successful entrepreneurial programs for the Eugene Area Chamber of Commerce, including Smart-ups Pub Talks and the Southern Willamette Angel Network.
Her program has spawned a young angel network that has evaluated more than 1, 000 businesses this year, brought 31 to investors, and ultimately wrote checks for seven.
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Envestors is a London-based angel network, which has over 1000 certified 'high net worth individuals' on its books who are looking to back early stage and start-up ventures.
When longtime entrepreneur and Columbia B-school adjunct professor Angela Lee founded 37 Angels, her eight-month-old angel network and initiative to train women to become investors, she began with a single stat.
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"This crisis has really brought to light the fact that lots of European banks heavily invested outside Europe, which is questionable in itself, " said Claire Munck, general manager of the European Business Angel Network.
After vertigo rendered him unable to fly a plane, Winfrey found another role for him, first with her charitable Angel Network rebuilding homes in post-Katrina New Orleans, then in South Africa, where he oversees day-to-day operations.
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"If you don't have any skin in the game, how can you expect angels to put up their own money, " says Katherine O'Neill, executive director of JumpStart New Jersey Angel Network, who attended the networking event last week.
There is a vibrant angel network.
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On the other side are representatives from Dish Network, Sky Angel, Netflix, Roku and Public Knowledge.
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In general, the best way to get in front of angel investors is by asking people in your network for introductions.
There has already been one spin-off, Angel, but that has stayed on the WB network.
Angel investing still relies on an old-boys network and closed-door conversations.
Walker sold his network security company to Network Associates, and is now looking to play angel.
Her first angel investor in the company was Allen DeBevoise, CEO of Machinima, the second largest video network on YouTube and mega-network for gamers.
He then struck a joint venture with Dish Network, under which Dish paid for the use of some of his frequencies and carried Sky Angel over its EchoStar III satellite.
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The venture world has long been a tightly-woven, self-perpetuating male-dominated network, with females making only 5 to 10% of venture capital partners and 15% of angel investors.
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