Typically, someone who is in agreement with you will smile andnod as you speak. (Disagreement shows up in compressed or pursed lips, clenched jaw muscles, or a head turned slightly away, so eye contact becomes sidelong.) But smiles are often used as a polite response and to cover up other emotions.
Slide the padlock icon to the right and it unlocks the handset, slide it to the left and you're dropped into the camera app (a clear nod to HTC's Sense 3.0 UI).