"Next week will be an important one for Terry and Lampard, " said Ancelotti.
Unless the plan is to replace Beckham and Donovan with Kaka and Lampard, which I must admit, will be interesting.
Malouda took advantage of more fine work from Zhirkov to beat Friedel, and Lampard completed his hat-trick with another penalty.
England looked the stronger side in early stages of the second half and Lampard rattled the bar with a free-kick.
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And a wonderful one-two between Ashley Cole and Lampard almost saw the former tee up namesake Joe to slide in a second.
The hosts did launch a late rally, with Everton defending desperately at times to keep out the likes of Alex, Drogba and Lampard.
O'Neill's side had degenerated into a shambles, and Kalou and Lampard inflicted further late punishment before Villa were put out of their abject misery.
Pompey looked set to frustrate Chelsea, but Marc Wilson mistimed a challenge on Branislav Ivanovic and Lampard converted from the spot 11 minutes from time.
Michael Ballack also saw red and Lampard scored a consolation penalty.
Deco and Lampard played a lovely one-two in the build-up to the England midfielder testing Doni's reactions with a 25-yard drive that was headed just inside the post.
Salomon Kalou was agonisingly close to scoring before Drogba and Lampard exchanged passes and the Golden Boot winner capped a fabulous season with the most important goal of his campaign.
The much-maligned Fernando Torres, back in the side because of injuries to Daniel Sturridge and Didier Drogba, flourished early on and almost set up goals for both Juan Mata and Lampard.
Ancelotti took positives from improved performances from senior players like Drogba, Michael Essien and Lampard, who have all been shadows of their former selves in recent weeks after battling back from injuries.
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Since interim manager Guus Hiddink took charge, however, the Blues have enjoyed a resurgence and Lampard has played a key role in their run of only one defeat in their last 13 matches.
Malouda rounded off a fine passing move with a sweet back-post finish to make it 2-0 and Lampard practically walked the ball into the net when he met substitute Nicolas Anelka's pass from another swift breakaway.
Centre-back Terry and midfielders Lampard and Essien are expected to play in Chelsea's next match against Arsenal on Monday and manager Carlo Ancelotti is adamant that the return of his star players will help keep the club's title defence on track.
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Suddenly, the Blues looked a hungrier and more purposeful outfit, with Ashley Cole and Jose Bosingwa providing width in the final third and Frank Lampard probing busily behind Didier Drogba, Nicolas Anelka and Florent Malouda.
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That match saw a change from the rigid 4-4-2 system previously favoured by Capello, and saw Barry used with Steven Gerrard and Frank Lampard in a central midfield triumvirate, with youngsters Adam Johnson and Theo Walcott employed on the flanks.
Torres failed to apply a touch to Drogba's effort and when Lampard looked certain to score from the rebound Evra made a desperate, and decisive, block.
But a famous win was cruelly snatched from them by late goals from Juliano Belleti and Frank Lampard.
Late goals from Juliano Belletti and Frank Lampard condemned City to a 2-1 defeat at Stamford Bridge on Saturday.
Joe Hart replaces David James in goal and Phil Jagielka and Theo Walcott are in for John Terry and Frank Lampard.
Nicolas Anelka and Frank Lampard each then poked in as Chelsea ran away with it, with Ipswich up next for the Blues.
The opening period suggested it would go to plan with Roma keeper Doni kept busy by shots from Deco, Florent Malouda and Frank Lampard.
Nicolas Anelka was twice narrowly off target and Frank Lampard should have done better than shoot straight at Edwin van der Sar following good work by Florent Malouda.
Of the other players who are missing, Spurs keeper Paul Robinson is out with a knee injury and Chelsea pair John Terry and Frank Lampard both need minor operations.
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Following the tackle Chelsea players Didier Drogba, John Terry and Frank Lampard all surrounded Riley appearing to bully him out of handing out a straight red for the tackle.
But it is the diminishing talent pool of young English players to succeed the likes of John Terry, Steven Gerrard and Frank Lampard that has been concerning Wilkinson most.
Chelsea were caught out by Alonso's quick free-kick and when Lampard failed to clear, Kuyt stole in on the end of Javier Mascherano's mis-kick to steer the finish past Cech.
Anelka made it three late on with a neat finish after good work from Lampard and Kalou, and there was still time for Lampard to add a fourth with a close-range finish from Kalou's pass.
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