The treatment, CYT387, appears to demonstrate an ability to render and maintain myelofibrosis patients transfusion independent for clinically-relevant periods, while also improving other symptoms, according to a phase I and phase II study.
For example, how will transplanted human iPS cell derivatives behave in terms of cell fate and safety long-term in clinicallyrelevant transplantation settings in rodents or larger animals that are good models for humans?
The companies ran the required test and in June said results showed Bydureon wasn't associated with a clinicallyrelevant prolonged measure of heart rhythm.