Friedhoff and Buxbaum have shown two things: First, they showed that lovastatin could prevent cells from making beta amyloid in the test tube in doses that could be realistically given to patients.

FORBES: Magazine Article

Another possibility is that researchers need to test the amyloid drug on earlier stage patients.

FORBES: Eli Lilly Alzheimer's Disease Failure Bolsters Amyloid Theory Skeptics

In the late 1980s circumstantial evidence that condemned the role of Alzheimer's amyloid plaques began to build when Bruce Yankner, a Harvard biologist, showed in test tubes that the amyloid protein poisoned brain cells.

FORBES: Magazine Article

In the late 1980s circumstantial evidence condemning the role of Alzheimer's amyloid plaques began to build when Harvard biologist Bruce Yankner showed, in test tubes, that the amyloid protein poisoned brain cells.

FORBES: Magazine Article

To be specific, Merck (MRK) will test a beta-amyloid precursor protein site-cleaving enzyme, or BACE, inhibitor, which the drugmaker notes is the first drug with this type of mechanism to advance to this stage of clinical research.

FORBES: Merck Makes A 'Speculative' Step Into Alzheimer's

They vote with their test tubes, and they have put their test tubes into a huge number of experiments over this amyloid hypothesis.

FORBES: Attacking Alzheimer's

The next year Golde, at the Mayo Clinic, and his collaborator Edward Koo, at uc, San Diego, showed--at least in the test tube--that high doses of ibuprofen and other anti-inflammatories could lower production of amyloid-beta-42, which was believed to be a bad type of amyloid.

FORBES: Executive Health