Five patients with a lethal leukemia achieved complete and rapid remissions after the treatment, in which cells from their own immune systems were genetically altered to specifically attack the disease.
He had found with a collaborator at Johns Hopkins that stem cells in mice genetically altered to have a similar disease did not respond normally to a signaling pathway called hedgehog that had an important role in brain development.
In a study, his group found that DHA fatty acids from fish oil could delay or deter the onset of Alzheimer's disease in rats or older mice that had been genetically altered to develop the condition.