Earlier, Ali Carter and Stephen Maguire also booked their places in the last 16.
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Also registering wins on Monday afternoon were Joe Perry, Mark King, Robert Milkins and Ali Carter.
BBC: SPORT | Other Sport... | Snooker | O'Sullivan books slot in last 16
The third man through to the last 16 is Irishman Ken Doherty, who beat Ali Carter 5-3.
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The 2006 world champion lost his opening match to Ali Carter and then came off second best against compatriot Marcus Campbell too.
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The Sale potter will be joined in the next round by Ali Carter , who won his first ranking event title last season when he beat Joe Swail in the final of the Welsh Open.
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