This disappearance of people with an E-4 gene from the aging population is a "remarkable finding, " say the University of Helsinki scientists who did the study.
We will routinely turn off genes that promote disease and aging such as the fat insulin receptor gene that tells the fat cells to hold onto excess fat.
Francis Collins, director of the National Institutes of Health and one of the discoverers of the gene that causes progeria, said the drug's usefulness for vascular stiffness in normal aging is an important question to study.