Zovant is an artificially created version of a naturally occurring protein called Activated Protein C.

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AstraZeneca is in midstage trials with 180 melanoma patients for a drug that hits a related target called mitogen-activated protein kinase kinase.

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AstraZeneca (nyse: AZN - news - people ) is in midstage trials with 180 melanoma patients for a drug that hits a related target called mitogen-activated protein kinase kinase.

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It appears to block the action of a protein called Stat 1, which becomes activated within cells after a stressful event such as a heart attack or stroke, and plays a role in inducing cell death.

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This second gene, activated whenever the gene for P16INK4A was active, produced a protein that was harmless in itself, but which could be made deadly by the presence of a particular drug.

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He found that once TGF-beta activated a cell, it triggered the CTGF gene to make its protein (see chart).

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Sharpening its efficacy, the gene therapy is not activated until a patient takes a pill, controlling how much of the protein is released at what time.

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The DNA is not activated until a patient takes a pill, giving further control of how much of the protein is released at what time.

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