Today, dozens of researchers and millions of dollars in funding support a mission to locate, activate and kill cells infected by dormant virus without harming patients.
"This is a custom made vaccine from the patient's own tumor cells which is designed to activate the patient's own defenses to fight the tumor where it had not done that before, " said NCI's Dr. Larry Kwak.
If hepatocytes and their genomes become disarrayed by disease, Willenbring says, it may activate oncogenes in the same way their experiment did, causing the cells to change identity and form cancers.