Schering wants to make this entirely about LDL (the bad cholesterol) and public health, but there is a valid scientific debate about the place of Zetia in the anti-cholesterol armamentarium.

FORBES: Schering Glitters, But Is It Gold?

But when he saw that Scandanavian study, James Liao wasn't immediately convinced about the benefits of LDL. He was surprised, because Zocor not only prevented heart attacks but also strokes.

FORBES: Magazine Article

Panelists wondered about the clinical effect of lowering LDL cholesterol from 400 to 300.

FORBES: FDA Panel Recommends Approval Of Mipomersen For Familial Hypercholesterolemia

On average, levels of LDL-C fell by about 25 percent during the first 26 weeks in those receiving the drug.

FORBES: FDA Approves Mipomersen For Homozygous Familial Hypercholesterolemia