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If your cancer is HER2 positive, you may also be given a targeted therapy to attack the protein that's overproduced in these cancers.
CNN: Recurrent breast cancer
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"To prove that a targeted therapy even worked was incredible a few years ago, " says Len Lichtenfeld, deputy chief medical officer of the American Cancer Society.
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And no drug company has yet perfected a standardized test to determine which particular genetic flaws lie behind an individual patient's cancer, a key prerequisite to targeted therapy.
FORBES: Conquering Cancer
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So far Innogene has produced TherCIM, a monoclonal antibody for targeted cancer therapy that is already marketed in Southeast Asia.
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Targeted therapy: Targeted therapy looks at whether the cancer cells respond to a group of drugs that block the growth and spread of cancer by interfering with the biology of the cancer cells.
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The work is significant because it goes a long way towards proving that the concept of gene-targeted therapy can work in major common tumors.
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That targeted cancer therapy, which helped most patients who took it for a rare leukemia, made it through the U.S. Food and Drug Administration in a lightning-fast three months.
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Insert Therapeutics and Intradigm are also working on targeted treatments, but both companies are also exploring the use of a Nobel Prize-winning therapy based on RNA interference (RNAi).
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Given the billions of cancer cells in a patient, some cells will likely evolve that lack the targeted genetic alterations or that are resistant to the targeted therapy.
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