But these memes aren't just about getting a laugh - they make a political point too, says Elsbeth Roundtree, a co-founder of Know Your Meme.

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The school's vice-principal (Richard Roundtree) menaces the hero like a cop grilling a smart-alecky gumshoe, and the distant sounds of cheer-leaders are heard as Brendan is pursued through the schoolyard by a knife-wielding goon.

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Ms. Roundtree, who works with teens in a school program, says she has lost several pounds, exercises regularly and follows a careful diet plan since getting her diagnosis.

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