But like a lava flow, casualties should be rare because the information and process is slow enough to allow escape.

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This story reveals a rare glimpse into the reality behind the closed doors of a highly secretive and PR-obsessed corporation, where information is tightly controlled.

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For instance, is the binding site just a rare variant, or does it contain mutations that have reduced the information so much that the protein can no longer recognise it?

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Among the exhibits at Crossrail's visitor information centre in St Giles High Street are medieval human bones found at Liverpool Street, a rare amber find and a piece of mammoth jaw bone.

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But the undercutting of business support services is not a rare occurrence and there are numerous ways of getting away with it, according to the senior executive of a large information technology services company who wished to remain anonymous.

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