Hassan met Saunders, then a PriceWaterhouseCoopers consultant, at a Leukemia and Lymphoma Society dinner when the younger man was doing work for Schering.
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The idea of using a leukemia drug for stomach cancer, an anti-seizure drug for nerve pain, a cancer drug for gout all were impactful suggestions proposed by physicians or researchers outside the company developing the drug.
That targeted cancer therapy, which helped most patients who took it for a rare leukemia, made it through the U.S. Food and Drug Administration in a lightning-fast three months.
One of the few medical doctors to lead a big drug company, Vasella saw potential in a new leukemia drug called Gleevec when others were skeptical.
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Five patients with a lethal leukemia achieved complete and rapid remissions after the treatment, in which cells from their own immune systems were genetically altered to specifically attack the disease.
Mr. Tebow proceeded to talk about spending time with a young leukemia patient from Florida who had just been transferred to hospice care and about how delighted Mr. Tebow was to say the kid's name on television and to let him know that someone cared.
The first of its two clinical-stage product candidates is a potential treatment for acute myeloid leukemia, a cancer that receives about 14, 000 new diagnoses in the U.S. annually.
Someone who is around a smoker inhales more benzene, a cause of leukemia, than he or she would inhale spending the same amount of time filling a car with gasoline.
In another path-breaking example, consider the case of Dr. Lucas Wartman, a young physician who developed adult acute lymphoblastic leukemia, a disease that is usually rapidly fatal, and for which there is no effective treatment.
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He found that when he transplanted a million human leukemia cells, full-scale tumors would almost always take hold in the mice.
Cephalon (nasdaq: CEPH - news - people ) sells a drug called Trisenox to treat a form of leukemia.
Cephalon sells a drug called Trisenox to treat a form of leukemia.
Their theory is that genetics and lack of exposure to germs play a strong role in determining whether a child develops leukemia.
These pills are becoming a mainstay of cancer treatment since the arrival of drugs like Tarceva, for non-small lung cancer, and Gleevec, for a form of leukemia.
Novartis is in final trials of a drug that may help the one-third of acute myeloid leukemia cases with a gene mutation that turns on cell-growth signals.
The hope for TGN1412 was to have it used to treat a rare form of leukemia.
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Cancer drug Gleevec gives chronic myelogenous leukemia patients a 24-month survival rate of 92%.
This designer approach resulted in one big winner, Novartis' Gleevec for chronic myelogenous leukemia and a rare stomach tumor called GIST.
So far, targeted drugs have produced dramatic advances for only a few less-common forms, including leukemia, certain stomach tumors and a subset of breast cancers.
Rowley's discoveries of chromosome abnormalities in leukemia secured a common agreement among scientists, physicians and the general public that cancer is, in fact, a genetic disease.
These so-called targeted therapies got their biggest boost from Gleevec, a Novartis drug for a rare form of leukemia, which some studies said helped 80% of patients.
His plan, though, hit a tragic snag on September 11, when Te'o lost both his grandmother and his girlfriend, the latter to a long battle with leukemia.
While Novartis has managed to profit from a string of cancer medicines, most notably Gleevec for a rare form of leukemia, most other drug companies have faced hurdles.
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There's good reason to rush: The white powder is an experimental drug called Glivec, and it may be the most potent weapon ever aimed at a common form of leukemia.
Patients who are successfully treated for HL continue to have this immune suppression and long term have a higher risk of leukemia and some other cancers because of their therapy.
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The widely publicized patient, Timothy Brown, was treated for leukemia with a bone marrow transplant that happened to come from a donor with a genetic mutation that makes immune cells resist HIV infection.
Cancer research "is a little like physics before Isaac Newton, " says evolutionary biologist Franziska Michor at Memorial Sloan-Kettering Cancer Center, who has devised a model of how leukemia cells respond to the drug Gleevec.
Some drugs, such as Gleevec, a treatment for a rare form of leukemia developed by Novartis (nyse: NVS - news - people ), can actually change the way a disease is treated.
The character was evidenced by being the team leader, a stellar student, a devout Mormon, and having played to perfection while overcoming the adversity of losing his 72-year old grandmother, and within a short time thereafter, his girlfriend, Lennay Kekua, who had Leukemia and died in a car crash.
Melanoma is a far more aggressive disease than leukemia, and some of the patients have already relapsed after just a few months.
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