It contains acid, mercury and other chemicals and has a great impact on residents' health.
By itself, the absence of the 80-mg dose probably wouldn't have a great impact on Crestor's sales, Arnold wrote.
The area of Bionics, for example, is an emerging scientific area that has a great impact on innovation.
Referring to the current dispute with Rio, President Tsakhiagiin Elbegdorj says that firms mining in Mongolia have a great impact on the country.
"It will have a great impact on people from the area because Thanet is a high unemployment area and there is not much chance of people finding jobs, " he said.
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Most watchers of the Supreme Court have similarly concluded that Justices Sandra Day O'Connor and Ruth Bader Ginsburg have had a great impact on their colleagues in cases of particular interest to women, such as abortion and sex discrimination.
That, I would argue, could have a great deal of impact on the midterm elections.
As part of building a strong company, we work hard at making Facebook the best place for great people to have a big impact on the world and learn from other great people.
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The Hacker Way As part of building a strong company, we work hard at making Facebook the best place for great people to have a big impact on the world and learn from other great people.
Whether it is my book or another, you will never find the Holy Grail of trading wisdom however with hard work and a great deal of persistence you will begin to pick up on nuances that can impact your trading a great deal.
And for the poor children who need it the most, the lack of access to a great preschool education can have an impact on their entire lives.
Inspired by the success of pioneers such as microfinance site Kiva and crowd funding sites like KickStarter and indiegogo, I expect that once the JOBS Act is fully enacted and allows for equity investments by unaccredited investors we will see a surge of specialized crowd funding sites with great positive impact on deserving individuals and new ventures.
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Just how great would be the adverse impact of such a development on intra-alliance relations is difficult to calculate with confidence at this point due to a number of imponderables.
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So, in keeping with local tradition we had a great lunch at Gates BBQ, while we engaged in a rigorous policy discussion on the elements of the Green Impact Zone and how it might be replicated around the country.
"Our revised estimates show that 2008 and 2009 saw the largest drops in giving in more than 40 years as a result of the Great Recession, exceeding previous recessions' impact on giving, " Edith Falk, chair of Giving USA Foundation, said in a statement.
There has been a great deal of debate about what impact the bull market has had on the real economy.
We recognize the impact a great teacher can make, and Partners in Learning is focused on empowering more than 8 million educators in over 114 countries to creatively and effectively use technology in their curriculum to help improve the way students learn.
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While this is a great list of games, it will be interesting to see what impact this has on the entire launch black eye.
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Admiral MIKE MULLEN (U.S. Navy): We get great questions, great engagement, and some of those things come back and have a significant impact on Navy policy.
While the terms of the settlement will remain confidential and are not anticipated to have a material impact on our financial results for 2012, this settlement is a great step forward in validating the value of our IP portfolio and the investments we have made in the mobile market.
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"Bradley's been going well and we have been looking at him as one for the future, but he certainly came on and made an impact for the Blues in what was a great win for them at the weekend, " said McBryde.
That uncertainty is itself a reflection of concern about the impact on the real economy of the aftermath of the great American boom of the late 1990s.
Scandals, on the other hand, make for great headlines, even though they usually impact a relatively small number of people.
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Add on top of that the recession -- the Great Recession, the near depression -- and you had a set of circumstances that had a negative impact on our deficit.
But, during this Great Recession, I felt more like a prisoner and I could see that my depressed state was having its impact on my team and even the company culture.
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