Limiting the losses on risky small-business lending requires a detailed understanding of local businesses.

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We were looking to continuously refine our hypothesis until we had a detailed understanding of the specific benefits and costs of our product to the costumer.

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In the long term, researchers hope that a detailed understanding of the genome's permutations will lead to a new era of customized medicine tailored to individual genetic codes.

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Mr McElheny made himself an insider, not by being invited in, but by patiently thinking his way into a detailed understanding of how Land and his company worked.

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In the long term, researchers hope a detailed understanding of the genome's permutations will lead to a new era of customized medicine, in which drug regimens, diagnostic tools and medical devices are tailored to individual genetic codes.

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"By the detailed examination, documentation and flow-charting of financial processes, executives will develop a more intimate understanding of the relationships of key variables and be more confident in their decisions, " writes Michael Fox in the Minneapolis Star-Tribune.

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