Timothy Anderson, an analyst at Prudential Equity Group, wrote in a note yesterday that liver toxicities seen with Prexige could be a commercial "deal killer" but that the results may help Merck.
Besides obviously needing a CableCard-ready TV set (most new digital HDTVs have to have CableCard slots), there are a few downsides, like you can't access your cable company's onscreen programming guide and you can't order pay-per-view or video-on-demand programming (at least not using your remote), but the real dealkiller for us is that you won't be able to use it with a digital video recorder.