AstraZeneca has doped its version of a COX-2 inhibitor with nitrous oxide--laughing gas--to soften the gastrointestinal blow.
Whereas a Cox presidency would be high on elegant deal-making, a Martin one would stress fair dealing.
Contrary to popular belief, a cox does not shout "in, out, in, out".
BBC: SPORT | Other Sport | Boat Race 2003 | Little things count
Vioxx, a Cox-2 made by Merck (nyse: MRK - news - people ), had cardiac precautionary language added to its label.
Nissen frets that Merck is comparing Arcoxia to diclofenac, a drug that itself is thought to be a Cox-2 inhibitor that poses some cardiovascular risk.
It was hypothesized, therefore, that a COX-2 inhibitor could be of value in eliminating these polyps and preventing colon cancer in people predisposed to such polyps.
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In early-stage human trials in May 2000, scientists observed 66% fewer stomach erosions in 31 patients treated with a nitrous oxide version of a COX-2 inhibitor versus naproxen.
Novartis (nyse: NVS - news - people ), which is developing a Cox-2 drug called Prexige, has decided on even bigger clinical trials than Merck.
Six chemists spent long nights paging through piles of dusty chemistry journals in the Monsanto library to see if anyone had invented a COX-2 inhibitor without realizing it.
For seven months potential crews (each with eight oarsmen and a cox) undergo two intense sessions every day, one on the water and one on indoor rowing machines or ergometers.
The new study, which is expected to be published in the British journal The Lancet in the next few weeks, is among the largest studies to date looking at a cox-2 inhibitors' safety profile.
"The crew don't treat me any differently from a male cox, " she says.
BBC: The rival coxes flank Cambridge rower Thorsten Englemann
BBC: The rival coxes flank Cambridge rower Thorsten Englemann
Cox Business is a facilities-based provider of voice, video and data solutions for commercial customers, and Cox Media is a full-service provider of national and local cable spot and new media advertising.
MEDAL, he says, should be "terrific" for demonstrating whether a more powerful Cox-2 inhibitor confers more risk to the heart than a weaker one.
More information about Cox Communications, a wholly owned subsidiary of Cox Enterprises, is available at www.cox.com and www.coxmedia.com.
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"Our action today is one of several that will make very clear the SEC is targeting hedge fund insider trading as a top priority, " Cox said in a statement.
"It has been in the family for a long time, " Mr. Cox told a Journal reporter in 2007.
They stop inflammation by blocking an enzyme called Cox-2 without also hitting a related enzyme called Cox-1.
The patient known only as Mother, (a brave performance by Catherine Cox) opens with a comical number about how annoying doctors can be, constantly asking her who the president is.
"'Furlough Friday' is a disgrace to our nation, " Cox said in a statement.
From a legal point of view, Mr Cox says, a case could be made that pension funds and other institutional investors are violating their fiduciary responsibilities when they do not try to get their money.
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The administration had considered Cox a prospect for the 9th Circuit Court of Appeals, but California Democratic Sen.
Steven Reid added to the West Brom lead with a header and a long range Cox strike secured their victory.
Christo wrote Cox a letter of recommendation to the Parsons School of Design in New York, where he enrolled in 1977.
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Fuels boss Patrick Davies, along with Cox a management member of the Sasol board, thinks the two foreign GTL facilities are key growth drivers.
Going forward, ball clubs might not be so willing to offer highly lucrative contracts to managers who lack the experience, credentials and intangibles of a LaRussa, Cox and Torre.
"We know that it causes problems from placebo-controlled trials, " says Garret FitzGerald, a pharmacologist at the University of Pennsylvania, who predicted early on there might be a risk with Cox-2 drugs.
What makes life different for a Boat Race cox is that, uniquely over this stretch of water, the crews are side by side, with nothing separating them except the view of the umpire.
BBC: SPORT | Other Sport | Boat Race 2003 | Little things count
Now, as cable's first-quarter earnings start to roll out on May 5 with a report from Cox Communications (nyse: COX - news - people ), strong results all around indicate that the promise of consistent free cash flow for all may finally materialize.
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