Germany's Paion is developing a clot-buster originally found in the venom of vampire bats.
Drugs like aspirin and clopidogrel (Plavix, NYSE:BMY) prevent platelets from clumping together into a clot.
When he went to a hospital, doctors found he had a clot in a lung, she said.
And nobody knows exactly what the trigger might be or how it is translated biochemically into a clot.
Its device uses a high-speed jet at the tip of a catheter to wash out a clot and then vacuum it out.
Another big hope: Alfimiprase, a clot-buster developed by San Carlos, Calif.
This wasn't a clot of esoteric names and dates I'd dozed through in high school history, like the Habsburg Succession or the War of Jenkins's Ear.
One is to pair a better clot-buster with a technique for selecting patients most likely to benefit from it.
The drugs work by blocking an enzyme called factor 10a that helps spur the production of a crucial clot-promoting protein called thrombin.
Researchers now believe that up to 85% of heart attacks occur when arterial plaques suddenly rupture, spilling toxic substances and triggering a massive clot.
During childhood, hemiplegia is often caused by a stroke, like Peter's, when a bleed or clot damages part of the brain.
The house first came to prominence in the early '70s, when a man named Bill Clot transformed his home in the Miami suburbs into an impressive Christmas display, a miniature village populated by mechanical Santas, reindeer, angels, penguins, villagers, elves and holiday lights.
WSJ: Embracing the Robo Elves of the Bill Clot Christmas Display | Traveler's Tale
You only have about three hours to get to the emergency room, go through the admission process and get evaluated before the doctors can figure out if you are a candidate for the clot busting drug that could save you from devastating disability.
When I was a kid in Miami, the Clot house was on my radar, of course, but mostly as a place to avoid.
WSJ: Embracing the Robo Elves of the Bill Clot Christmas Display | Traveler's Tale
Even though I grew up a mile away from the Clot house, I didn't visit it until my 30s.
WSJ: Embracing the Robo Elves of the Bill Clot Christmas Display | Traveler's Tale
After stripping out known risk factors such as smoking, diabetes and cholesterol, a pattern between body shape and clot risk emerged, independent of body weight alone.
Tests revealed the clot, and doctors used a vein from his groin area to widen the artery during July 13, a procedure to prevent future clots.
Doctors can break up the clot by using Activase, a drug used by Genentech (nyse: DNA - news - people ), but that drug must be used quickly after the stroke happens.
The average clot size of those who smoked a cigarette in the six hours before their heart attack was 23 square millimetres.
Dr Thiemann says there are several possible reasons for differences between the new findings and the conventional wisdom, which was based on research trials of clot-busting drugs conducted about a decade ago.
For now, treatment of strokes is pretty much limited to Genentech's clot-busting drug, Activase, a tissue plasminogen activator, which is primarily used to treat heart attacks.
New clot-busting drugs allow some stroke patients to make a full recovery if treated within three hours of their attack.
In those who had smoked a cigarette between six and 24 hours before their attack the average clot size was 12.5 square millimetres.
Their hope is that such a drug would be precious to patients with ischemic strokes and, unlike clot-buster drugs, harmless to those with hemorrhagic strokes.
Premature deaths from heart disease - the single biggest killer - are down by a quarter since 1997, with a third more heart operations, twice as many patients receiving immediate access to clot-busting drugs and cholesterol lowering drugs now prescribed to 1.8 million people.
BBC: NEWS | UK | Politics | Full text: Blair on public services
One study found that chest-pain patients who were treated aggressively -- with, say, angioplasty, cardiac bypass or sophisticated clot-busting drugs -- did better than those whose doctors took a "wait and see" approach.
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