In a big leap for medicine, gene sequencing helps doctors treat a sick infant.
Rudel's critics say it's a big leap from monkey arteries to deciding what humans should eat.
Put it on the iPad 2, however, and gamers will notice a big leap in graphics.
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Apple, for example, reached No. 47 this year, a big leap from 75 last year.
So even a small loss of output can lead to a big leap in the price.
Still it's a big leap for the Signature from its former home base, where there were just 160 seats.
WSJ: Frank Gehry | Pershing Square Signature Center | By Julie V. Iovine
It is a big leap, though, from a slowing economy and a crafty regulator to a systemic bad-debt problem.
That is a big leap of faith for one wonders how the Greeks would gain access to the capital markets again.
The first real-world tests are now confirming that the iPhone 5 download speed is a big leap up from the iPhone 4S download speed.
Sure, it's not the most exciting update to Samsung's camera line, but it's clearly a big leap up from the NX1000 -- on paper, anyway.
As adaptive cruise controls, self-parking options and automated-braking systems gradually become more capable and widespread, it is not a big leap to full autonomous control.
Mobile gaming on the iPhone or iPod touch takes a big leap forward with the iFrogz Caliber Advantage, a tactile, analog game controller that directly attaches to the mobile device.
ENGADGET: iFrogz's Caliber Advantage iPhone 5 gaming case hands-on
Combine these two ideas and look at them against a backdrop of the developing world making a big leap forward economically and you have the recipe for a longer-term bull trend.
Also, it could be a stretch, but the sponsorship might actually help mesh the fan base of more urban sports, like basketball, and racing, which would be a big leap racially.
But it is a big leap from the laboratory to the real world - whatever our telomeres may say, human lifespans also have to contend with additional factors like diet, drink and stress.
This is a big leap forward for the Windows ecosystem as not only is one of the top game engines now available for developers to begin working with, it is also the full PC implementation.
ENGADGET: NVIDIA, Epic Games bringing Unreal Engine 3 to Windows 8 and Windows RT (video)
The IT Secretary said that the Andhra Pradesh has reached a critical phase in the terms of growth in the sector and was poised to make a big leap forward in the coming months and years.
BBC: News | SOUTH ASIA | Andhra Pradesh claims huge IT growth
Provided the researchers can keep refining the project, we could be looking at a big leap in solar power efficiency with very little extra footprint, something we'd very much like to see on the roof of a hybrid sedan.
But It'll take a pretty big leap of faith from cynical supporters who have already started to vote with their feet.
Activision has taken a big creative leap with X-Men Destiny, the first Marvel game to introduce three brand new members of the X-Men.
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"It would be a pretty big leap from trying to figure out how to partner around the world to we're going to do it ourselves, " Del Prete says.
It understands that an entirely different eurozone and European Union may be needed to save its currency, but it shies away from a "big leap" that might not have the backing of the people.
But a big factor in the leap is a recent decision to begin paying salaries to staff.
Is it such big a leap to think consumer electronics beyond smart phones can be used for payments?
And given this, how big a leap is it for companies to mock themselves as a means to reach audiences?
Pure electric vehicle might be too big a leap for consumers.
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"If you wear a khaki suit during the summer, it isn't that big of a leap to wear mauve, " said Josh Peskowitz, men's fashion director at Bloomingdale's.
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Even though "Hardbody" still needs quite a bit of revision before making the big leap, it bears the unmistakable marks of a musical that is at once charmingly quirky and genuinely affecting, the same mix that made "Once" a sleeper hit.
Because business is so social, this quantum leap is a big deal.
As the German economist, Christian Schultze, told me for my television bulletin on Thursday, Gemany is not ready for collective European bonds - or any big leap towards a full fledged Federal union.
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