He's never very happy at the best of times—he'll be much worse now!
他即使在情绪最好的时候也从未很高兴过，现在就更糟了！
At the close of the previous century, ambitions for malaria control had been reduced to holding the disease at bay, aiming to keep a very bad situation from getting any worse.
在上个世纪结束之际，疟疾控制方面的远大目标已被降至保持疾病稳定，其目标是保证其糟糕的境况不再变得更坏。
We are naturally skeptical of the unknown and, of course, there is always a chance we might not be very good at it, or even worse, might look silly while trying.
我们对于未知事物有天然的怀疑，而且，我们当然可能对其并不擅长，或者更糟的是，在尝试时洋相百出。
At the very least, Funny or Die has managed to harness the explosion of comedy on the Web, give it a professional coat of paint and bring it - for better or worse - some Hollywood cachet.
“滑稽还是死亡”努力控制着网上的喜剧爆炸现象，至少给它涂上了一层职业化的外表——某种好莱坞的身份。
"The property sector has probably already reached a tipping point given the data is getting worse at a very fast pace," Zhang said.
“数据正快速的恶化，房地产业已经到达一个临界点”张表示。
China and Russia are in a very poor position monetarily, at least as bad as Europe and the us, perhaps even worse.
中国和俄罗斯是在一个非常贫困的立场金钱，至少有一样糟糕欧洲和美国，甚至可能更糟。
He's never very happy at the best of times -he'll be much worse now!
他即使在情绪最好的时候也从未高兴过，现在就更糟了。
A very painful run at a college degree from a no-name school that is much worse than the one I quit six years ago.
还有在一个没有名气的甚至比我六年前退学的大学还糟的一个学校痛苦地混一张大学文凭。
But at many moment, many person are very difficult to achieve the self-adjustment, and make themselves likes animal, even more worse than animal.
可是有不少时候，不少人很难做到自我调整，也就是使得自己跟动物一样，甚至是比动物更糟糕。
You'd better not bother him now. He's never very happy at the best of times-he'll be much worse now.
你最好现在别去烦他，情况顶好时他也从未高兴过，那现在可要糟多了。
The medical people looked at him. I don't think it's anything special but it was getting worse and on Saturday morning he almost couldn't move. The muscle was very tight.
医生给他看了一下，我觉得没什么事，但是病情却突然恶化了，周六早上他几乎快不能动了，肌肉感到严重的抽筋和疼痛。
Researchers like Pope and Morgan may look at the data very differently, but they agree about one thing: heavy boozing is worse for your neurons than dope.
波普和摩根等研究人员可能对数据的看法有很大的分歧，但是他们都同意一件事：酗酒对你的神经细胞的影响比吸毒更糟糕。
The Queen was dreadfully fat and had a double chin and a fat, powdered face - which isn't a very nice thing at the best of times, and of course looks much worse when it is ten times too big.
王后胖得吓人，双下巴，一张擦着粉的胖脸——即使在最好的情况下，这都不是件好事，而这张脸又大了十倍，当然看上去就更糟了。
The Queen was dreadfully fat and had a double chin and a fat, powdered face - which isn't a very nice thing at the best of times, and of course looks much worse when it is ten times too big.
王后胖得吓人，双下巴，一张擦着粉的胖脸——即使在最好的情况下，这都不是件好事，而这张脸又大了十倍，当然看上去就更糟了。
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