Conclusion PCNA antisense RNA can significantly suppress the in vitro growth of gastric cancer cell line.
结论pcna基因反义rna对胃癌细胞的生长具有明显的抑制作用。
Objective to observe the effects of antisense RNA of connective tissue growth factor (CTGF) on rat liver fibrosis.
目的观察结缔组织生长因子(CTGF)反义rna对实验性肝纤维化的影响。
With the discovery of antisense RNA and further research, antisense RNA technique has been applied in the study of gene regulation.
随着反义rna的发现及对其研究的深入,反义rna技术已被广泛应用于基因调控的研究中。
Objective: to study the effect of VEGF antisense RNA on the proliferation activity and apoptosis of human pituitary adenoma cells in vitro.
目的:研究血管内皮生长因子(VEGF)反义rna对体外培养人脑垂体瘤细胞增殖和凋亡的影响。
Results: After the transfection, antisense RNA had been successfully expressed respectively, and NK cells activity had been improved about 15%.
结果:转染后反义rna均得到高水平表达,并使NK细胞的杀伤活性提高约15%。
AIM: to construct eukaryotic antisense RNA expression vector of CD147 and probe into a new method to treat invasion and transfer of osteosarcoma.
目的:构建CD 147反义rna表达质粒载体,探索治疗骨肉瘤侵袭和转移的新方法。
CONCLUSION CD147 antisense RNA can inhibit invasion and tumorigenesis of ovarian cancer cells and CD147 may become a new drug target of tumor therapy.
结论CD147反义核酸能抑制卵巢癌的转移和成瘤,因而有可能成为卵巢癌的治疗的药物靶点。
Objective To observe the effect of proliferating cell nuclear antigen (PCNA) antisense RNA on the growth characteristics of human gastric cancer cell.
目的观察增殖细胞核抗原(pcna)基因反义rna表达质粒对人胃癌细胞生长特性的影响,探讨其抗肿瘤作用。
Objective To explore the effects of endothelin converting enzyme-1 (ECE-1) antisense RNA on ECE-1 expression in human bronchial epithelial cell line(16HBE).
目的研究内皮素转换酶-1(ECE -1)反义RNA对人气道上皮细胞ECE -1表达的抑制作用。
This paper presents the definition and action mechanism of antisense RNA; Besides, the paper reviews antisense RNA technology and its application in agricultural field.
介绍了反义rna的概念及作用机理,对反义rna技术及其在农业领域的应用进行了概述。
It was investigated that over-expression of P33ING1 could promote apoptosis induced by lack of serum, and transfection antisense RNA could suppress apoptosis induced by lack of serum.
有研究表明P 33ing1的过表达可促进由“血清饥饿”诱导的细胞凋亡,而转染反义rna则可抑制“血清饥饿”导致的细胞凋亡。
Objective To investigate the effect of dual-target antisense RNA of hepatitis B virus (HBV) targeted to X and P region on replication and expression of HBV gene in HBV transgenic mice.
目的探讨针对乙型肝炎病毒(HBV)x、p双靶区反义RNA对乙型肝炎病毒转基因小鼠HBV复制和表达的影响。
Antiviral activitity of the antisense RNA was evaluated by cytopathic effect using cultured IBRS2 cell and anti- IBRS2 cell infected by TGEV respectively, and the inhibitory rate was about 50%.
通过TGEV分别感染IBRS2和IBRS2抗性细胞产生的病变,结果表明该反义RNA对病毒的复制有抑制作用,其抑制率近50%。
People utilize this characteristic of antisense RNA to adjust effectively the biological gene in the fields of animals and plants, microorganism and medicine etc. It has made the excellent success.
目前人们利用反义rna这一特点,在动植物、微生物以及医药等领域对生物基因进行有效调控,取得了令人瞩目的成就。
Antisense RNA exists in all kinds of living beings wildly. It ACTS on the course of the replication of DNA, transcription and translation, which realize the regulation and control of gene expression.
反义rna广泛存在于各类生物中,它作用于DNA的复制、转录、转译的过程,实现对基因表达的调控。
Antisense RNA exists in all kinds of living beings wildly. It ACTS on the course of the replication of DNA, transcription and translation, which realize the regulation and control of gene expression.
反义rna广泛存在于各类生物中,它作用于DNA的复制、转录、转译的过程,实现对基因表达的调控。
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