Objective:To detect the expression of glycosyl phosphatidyl inositol (GPI) anchored protein on the blood cell membrane and its implication in the diagnosis of paroxysmal nocturnal hemoglobinuria(PNH).
目的:探讨血细胞膜表面糖基磷脂酰肌醇(GPI)锚蛋白分子表达异常在诊断阵发性睡眠性血红蛋白尿症(PNH)时的意义。
Cell-surface engineering technique, also named as GPI-anchored protein transfer, has become an attractive strategy to express new proteins on cell membranes without gene transfer.
细胞表面工程,又称GPI锚定蛋白转移法,是一种不依赖基因转移而能够在细胞膜上表达新蛋白的有效方法。
This method involves purified glycosyl-phosphatidylinositol (GPI)-anchored proteins which can spontaneously incorporate their lipid tail into cell membranes.
GPI锚定蛋白可以通过其尾部脂质GPI结构自然地整合到细胞膜上。
This method involves purified glycosyl-phosphatidylinositol (GPI)-anchored proteins which can spontaneously incorporate their lipid tail into cell membranes.
GPI锚定蛋白可以通过其尾部脂质GPI结构自然地整合到细胞膜上。
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