A team led by Courtine used drugs known as serotonin agonists to awaken the walking circuits in paralysed rats whose spines had been severed.
据刊登在《自然—神经学》(Nature Neuroscience)杂志上的一份报告所述,由库尔蒂纳带领的研究小组对脊髓完全受损的瘫痪老鼠进行了实验,实验中采用叫做血清素致效剂(serotonin agonist)的药物,来唤醒瘫痪老鼠的步行回路。
Victoza is in a class of medicines known as glucagon-like peptide-1 (GLP-1) receptor agonists that help the pancreas make more insulin after eating a meal.
利拉鲁肽是一种GLP - 1受体激动剂,这类药可在用餐后促使胰腺分泌更多的胰岛素。
What are the sedative effects of alpha 2 agonists?
2受体激动剂的镇静效果机理是什么?。
The establishment of yeast-based screen platform for PPAR agonists and antagonists.
基于酵母水平PPAR 激动剂和抑制剂筛选模型的建立;
The receptors, and agonists and antagonists thereof, may be used to treat bone diseases.
所述受体、其激动剂或拮抗剂可以用来治疗骨疾病。
TLR3 agonists, as immunoadjuvant, have been applied for adjuvant immunotherapy of some tumors.
TLR3激动剂作为免疫佐剂已应用到某些肿瘤的辅助性免疫治疗。
Low dose levodopa and dopamine agonists are effective in controlling most symptoms of the disorder.
小剂量左旋多巴和多巴胺激动剂治疗有效。
So far, one third of approved small molecular drugs sold in market are the agonists or antagonists of GPCR.
目前世界药物市场上有三分之一的小分子药物是GPCR的激动剂和拮抗剂。
Rosiglitazone belongs to a class of drugs known as peroxisome proliferator-actiated receptor (PPAR) agonists.
罗格列酮属于称为过氧化物酶体活化受体(PPAR)促效剂一类药物。
The results showed that GABA receptor agonists increased rat's pt, and GABA receptor antagonists decreased pt.
结果表明,GABA受体激动剂可提高大鼠痛阈,而拮抗剂降低大鼠痛阈。
Efficacy of 5-ht3 antagonists and 5-ht4 agonists in irritable bowel syndrome: systematic review and meta-analysis.
肠易激综合症5 - HT 3受体拮抗剂和5羟色胺受体激动剂的疗效:系统性回顾和荟萃分析。
AIM to study the effects of dopamine receptor agonists on ethanol induced striatal ascorbic acid (AA) release in rats.
目的研究多巴胺受体激动剂对乙醇引起大鼠纹状体抗坏血酸(AA)释放的影响。
CONCLUSIONS Weight reduction with GLP-1 receptor agonists was associated with a shift toward a more favorable cardiovascular risk profile.
结论:GLP - 1受体激动剂治疗后的体重减轻与心血管危险因素谱向更有益的方向转变有关。
The aim of the present study was to assess the prevalence of valvular heart disease in patients treated with dopamine agonists for prolactinomas.
目前的研究目的是评估使用多巴胺激动剂治疗的泌乳素瘤病人瓣膜性心脏病的患病率。
Stimulation of tryptase release from mast cells by tryptase receptor agonists indicated that tryptase can stimulate mast cells in a positive feedback way.
而类胰蛋白酶受体激动剂对肥大细胞类胰蛋白酶分泌的促进作用则表明类胰蛋白酶是肥大细胞激活的正反馈性刺激剂。
So, Spiegelman and colleagues undertook studies to determine whether PPAR agonists might be useful as adjuvant therapy with currently used chemotherapeutics.
因此,Spiegelman和他的同事着手研究以确定PPAR激动剂是否可以作为目前化疗的有用的辅助治疗。
Here we show that charged sodium-channel blockers can be targeted into nociceptors by the application of TRPV1 agonists to produce a pain-specific local anaesthesia.
结果显示,应用TRPV 1激动剂能够使带电的钠通道阻断剂特异性地作用于疼痛感受器神经元而产生特异性局麻止痛效果。
In vitro results suggest that dopamine agonists may have the potential neuroprotective effect because of the properties of antioxidation and scavenging radical oxygen.
体外研究的资料指出多巴受体激动剂有抗氧化,清除自由基的性质,可能有一定的神经保护效应。
LHRH agonists provide an additional class of agents for treatment of premenopausal women with hormone-receptor-positive breast cancer. Optimum duration of use is unknown.
LHRH激动剂为激素受体阳性的绝经前乳腺癌女性患者提供了一种附加的治疗手段。最佳服用时限仍未知。
Objective to investigate the actions of protease-activated receptor 1 (PAR1) agonists and thrombin on the secretion of interleukin-8 (IL-8) from human lung epithelial cells.
目的探讨蛋白酶激活受体1 (PAR1)激动肽和凝血酶对人肺上皮细胞白细胞介素- 8 (IL - 8)分泌的影响。
International Diabetes: Some research has indicated that metformin could increase the effects of GLP-1. Do you know of any cooperative effect of GLP-1 agonists and metformin?
《国际糖尿病》:一些研究表明,二甲双胍可以增强GLP - 1的药效。你是否了解关于GLP - 1激动剂与二甲双胍联合治疗的疗效?
Objective: Treatment with ergot-derived dopamine agonists, pergolide, and cabergoline has been associated with an increased frequency of valvular heart disease in Parkinson's disease.
目的:使用麦角衍生的多巴胺激动剂,已经证实帕金森病人使用培高利特和卡麦角林可能增加瓣膜心脏病。
Eugenol, cinnamic alcohol, phenyl methyl alcohol and phenyl ethyl alcohol have shown to be potential antagonists or partial agonists to octopaminergic receptors in pharmacologic studies.
一些含羟基芳香族植物精油类化合物对美洲大蠊的毒理学研究表明它们是章鱼胺受体的部分激动剂或拮抗剂。
Strong evidences exist to support the use of 5-ht_ (2c) receptor agonists as pharmacological treatment of many diseases, including obesity, drug abuse, anxiety, depression, OCD and epilepsy.
大量研究证据表明,5 - HT _ (2c)受体激动剂可能在治疗肥胖、焦虑、抑郁、强迫症和癫痫等疾病方面有疗效。
Conclusion visual hallucination is a common non-motor symptom among patients with PD, and cognitive function, disease severity and usage of dopamine agonists may be related to visual hallucination.
结论视幻觉是PD患者常见的一种非运动性症状,认知功能、病情严重程度、多巴胺激动剂的使用可能与视幻觉的发生有关。
Agonists of PPAR, a member of the nuclear hormone receptor family of transcription factors, are widely used in the treatment of type II diabetes and are relatively non-toxic.
PPAR激动剂,是细胞核激素受体家族转录因子的一个成员,被广泛用来治疗II型糖尿病,而且相对无毒。
Agonists of PPAR, a member of the nuclear hormone receptor family of transcription factors, are widely used in the treatment of type II diabetes and are relatively non-toxic.
PPAR激动剂,是细胞核激素受体家族转录因子的一个成员,被广泛用来治疗II型糖尿病,而且相对无毒。
应用推荐