The catalytic center of an enzyme is composed of a set of amino acids whose three-dimensional arrangement forms the "active-site" that allows them to efficiently bind and modify the substrate.
酶的催化中心是由一组氨基酸组成,其三维结构形成活性位点,允许它高效地结合或修饰底物。
Basic single-chain polypeptide that inhibits numerous serine proteases by binding to the active site of the enzyme, forming tight complexes.
基本的单链多肽,通过与酶的活性位点紧密结合形成复合物,抑制大多数的丝氨酸蛋白酶。
Chemical modification studies showed that the sulfhydryl, guanido, amino, carboxyl and indolyl groups may participate in the active center of the enzyme.
化学修饰实验发现:巯基、胍基、氨基、羧基和吲哚基可能参与酶活性中心的组成。
Copper is one of essential trace elements for human, acting as an active agon of lysyloxidase which is critical enzyme for collagen maturation.
铜是人体必需的微量元素之一,是胎膜中胶原纤维发育成熟的关键酶赖氨酰氧化酶的活性辅基。
Irreversible inhibitor of Thrombin and other serine proteases. Inhibits by acylation of the active site of the enzyme. Much less toxic than PMSF and DFP.
凝血酶及其他丝氨酸蛋白酶的不可逆抑制剂,将活性位点酰基化。比PMSF和DF P毒性小得多。
Enzyme engineering technology can improve the extraction and separation efficiency as well as transformation of active components in traditional Chinese medicine(TCM).
利用酶工程技术,可以提高中药有效成分的提取率,促进微量活性成分的转化。
Soil respiration and active microbiomass were good indexes of soil microbial characters and soil enzyme.
土壤呼吸和土壤活跃微生物量是衡量土壤微生物特性和土壤酶的较好指标。
A mechanism in which the active site of the enzyme does not change shape during catalysis.
一种在催化反应中酶活性位点形状不发生改变的机理。
The metal ion may be the catalytic center of the cofactor, or it may serve to bind the enzyme and substrate together to hold the enzyme in a catalytically active conformation.
金属离子可以是辅助因素的催化中心,也可以帮助形成酶活性所必须的构象。
Objective To study the effects of phosphate on guanidine denaturation of human placental alkaline phosphatase (HPAP) and provide a theoretical basis for flexibility hypothesis of enzyme active sites.
目的观察磷酸盐对人胎盘碱性磷酸酶(HPAP)胍变性的影响,为酶活性部位的柔性理论提供证据。
This finding led the researchers to conclude that all three active sites are essential for the proper functioning of the enzyme.
这项发现使研究者总结道,所有三种活性部位对酶发挥正常功能都是必要的。
Nattokinase, the main active ingredient of natto, is a potent fibrinolytic enzyme and has a potent protein structure made up of a single polypeptide chain consisting of 275 amine acids.
纳豆激酶,纳豆的主要活性成分,是一种强纤维蛋白溶解性酶,且含有一种由275种氨基酸组成的单个多肽链强蛋白结构。
Some irreversible inhibitors even become covalently bound to amino acids in the active site of the enzyme as they are brought through the early chemical steps of catalysis.
一些不可逆抑制剂,甚至成为共价结合的酶的活性部位的氨基酸,因为他们带来的是通过早期的催化化学步骤。
Several enzymatic methods, including enzyme catalyzed enantioselective synthesis and kinetic resolution, for the preparation of optically active cyanohydrins are reviewed.
综述了酶催化立体选择性合成及动力学折分制备旋光性氰醇的几种方法。
CONCLUSION Active recombinant human CYP2B6 obtained using baculovirus expression system will facilitate further examination of the role of this enzyme in drug metabolism.
结论杆状病毒表达系统能成功表达有活性的CYP2B6重组酶,可用来进一步研究在药物代谢中的作用。
Saccharifying enzyme and active dry yeast and cellulase were added in the process of liquid fermentation of residual dis-tillers grains of yellow rice wine for alcohol production.
添加糖化酶、活性干酵母和纤维素酶进行黄酒残糟液态发酵和蒸馏生产酒精。
This article introduces the application of hydrolases, oxidoreductases and their enzyme sources in the synthesis of optically active drugs.
本文介绍水解酶、氧化还原酶及其酶源在光学活性药物合成中的应用。
The main route for obtaining optically active alcohols is resolution of racemic alcohols catalyzed by enzyme in organic solvents by the esterification reaction.
有机相中应用酯化反应,酶法催化拆分消旋醇是获得光学活性醇的重要途径。
The paper studies Aniline -GOD electropolymerization with polyaniline as modified film and gains preparing conditions of high active enzyme electrode.
用苯胺作为修饰膜,研究了苯胺GOD电聚会固定,确定了制备较高酶活力电机的条件.。
This is an enzyme that converts a drug called 5-fluorocytosine (5-fc) into an active chemotherapy drug, 5-fluorouracil (5-fu), but only in the immediate vicinity of the stem cell.
胞嘧啶脱氨酶是一种能够将叫做5 -氟胞嘧啶(5 -FC)的药物转化为活跃的化疗药物5 -氟尿嘧啶的酶,但这种情形只发生于干细胞的紧邻。
Modification of the substrate by an enzyme can then be monitored electrochemically by means of the redox-active group.
随后可以通过氧化还原活性基团电化学监测酶对底物的修饰。
The carotenoid pigments of wheat flour are bleached by the addition of enzyme-active soy flour.
小麦面粉中的类胡萝卜素会由于添加具有酶活性的大豆粉的作用而褪色。
The Aloe contains a number of active principles such as anthraquinone compounds, polysaccharide, organic acid, amino acid, mineral elements and active enzyme.
芦荟含有蒽醌类化合物、多糖、有机酸、氨基酸、矿质元素活性、酶等多种有效成分,本文阐述了各有效成分的药理和保健功效。
These results showed that the ionizing group of the enzyme active center is the carboxyl group.
化学修饰法研究进一步证明侧链羧基是酶的必需基团,并测定出酶活性必需的羧基数为一个。
By use of enzyme chemical reaction method to determine the variations of serum bile acid level in 413 cases with virus hepatitis during both active and convalescent stages.
用酶偶联化学反应方法检测413例各型病毒性肝炎患者活动期和恢复期血清胆汁酸含量变化。
Angiotensin I is then cleaved to form active angiotensin II by ACE, a zinc-containing enzyme located in the endothelial lining of the vasculature of the lungs.
然后血管紧张素i在血管紧张素转换酶作用下变为血管紧张系II,血管紧张素转换酶是一种位于肺部血管内皮的含锌酶。
For instance, they might construct a compound that inhibits the active site of an enzyme crucial to viral reproduction.
举例来说,他们可以设计某个化合物,作用在病毒复制时不可或缺的酵素活性区,而加以抑制。
The highland barley green is rich in protein, vitamin, mineral, active enzyme, chlorophyll, etc, and it is the elite of the seedling of wheat in the highland barley.
青稞麦绿素富含蛋白质、维生素、矿物质、活性酶、叶绿素等多种有效成分,是青稞嫩苗的精华。
This article introduces the application of hydrolases, oxidoreductases and their enzyme sources in the synthesis of optically active drugs. 29 references are presented.
本文介绍水解酶、氧化还原酶及其酶源在光学活性药物合成中的应用。
This article introduces the application of hydrolases, oxidoreductases and their enzyme sources in the synthesis of optically active drugs. 29 references are presented.
本文介绍水解酶、氧化还原酶及其酶源在光学活性药物合成中的应用。
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