某药物一起使用时的会产生有害影响,不应组合使用(例如司他夫定和齐多夫定)。
A few drugs have harmful effects when used together and should not be combined (an example is stavudine and zidovudine).
建议使用毒性更小但效果相同的齐多夫定(AZT)或泰诺·福韦(TDF)作为替代品。
Zidovudine (AZT) or Tenofovir (TDF) are recommended as less toxic and equally effective alternatives.
一项研究表明,与服用安慰剂妇女25%的传染率相比,使用齐多夫定的产妇垂直传染率被减少到8%。
A study shows it cuts the rate of maternal transmission to 8% - in women taking a placebo the rate was 25%
齐多夫定会竞争性抑制司他夫定的磷酸酰化,因此禁止与齐多夫定联合用药。
Zidovudine may competitively inhibit the intracellular phosphorylation of stavudine. Therefore, use of zidovudine in combination with Stavudine is not recommended.
本发明涉及一种聚乙二醇修饰齐多夫定缀合物及其制备方法与应用。
The present invention relates to one kind of polyethylene glycol modified zidovudine conjugate and its preparation process and application.
本发明公开了齐多夫定脂质衍生物在治疗与病毒有关疾病药品中的应用。
The invention discloses application of zidovudine lipid derivative in medicaments for treating virus associated diseases.
目的考察齐多夫定棕榈酸酯及其脂质体在小鼠各组织中的降解动力学。
Objective To investigate the degradation pharmacokinetics of azidothymidine palmitate and azidothymidine palmitate liposomes in different homogenate of mice.
目的考察齐多夫定棕榈酸酯及其脂质体在小鼠各组织中的降解动力学。
Objective To investigate the degradation pharmacokinetics of azidothymidine palmitate and azidothymidine palmitate liposomes in different homogenate of mice.
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