其中骨髓源性干细胞因其取材方便,内涵丰富,日益成为基础研究和临床研究治疗的热点。
Bone marrow -derived stem cell which has the advantages of based convenience and rich contents, has increasingly become the hot spot in basic research and clinical studies.
文章就骨髓源性肝干细胞的分离、培养、纯化、诱导分化、检测及肝内移植的可能机制和应用前景进行综述。
The article covers isolation, culture, differentiation, tests, possible mechanisms of engraftment in the liver and application prospect of bone marrow-derived liver stem cells.
目的:研究骨髓源性神经干细胞在体外培养及诱导分化条件下能否分泌去甲肾上腺素(NE)。
Objective: To study whether the neural stem cells derived from bone marrow stromal cells (BMSCs) could excrete neural biological activity material-noradrenaline (ne) in vitro.
目的寻找骨髓源性肝干细胞的表面标记,进行定向分化及脾内移植研究。
Objective To identify the surface marker of bone marrow-derived liver stem cells, isolate the stem cells, and investigate the differentiation and intrasplenical transplantation of the stem cells.
方法对骨髓源性神经干细胞的培养上清分别进行无菌试验、支原体检测、热原质检测和异常毒性试验。
Methods Sterility test, mycoplasma detection, pyrogen detection and abnormal toxicity test were performed respectively on culture supernatant of neural stem cells from bone marrow.
结论:骨髓间充质干细胞移植后可能通过上调脑源性神经营养因子的表达从而促进脊髓损伤区神经元轴突的再生。
CONCLUSION: BMMSCs can promote the regeneration of neuron axon of spinal injury region after transplantation through up-regulating the expression of BDNF.
目的探讨利用肝损伤早期和淤胆血清培养体系从大鼠骨髓细胞中筛选、诱导分化和扩增肝干细胞亚群,以快速、高效地获取骨髓源性肝干细胞。
More and more reports about the application of liver stem cells in hepatic diseases appeared, especially about bone marrow-derived liver stem cells isolated from bone marrow.
研究骨髓间充质干细胞在体外诱导分化为肌源性细胞的可行性。
To investigate the feasibility of inducing marrow mesenchymal stem cells into myogenic cells in vitro.
目的探讨骨髓源性肝干细胞(BMDLSC)移植对肝纤维化病变的影响。
Objective To explore the action of transplantation of bone marrow-derived liver stem cells(BMDLSC)on hepatic fibrosis induced by alcohol in mice.
目的:探讨人骨髓源干细胞向具有功能的胰岛素分泌细胞分化的可能性。
AIM: To explore the possibility of differentiating functional insulin-producing cells from human BM-derived stem cells.
目的:观察骨髓基质细胞源性神经干细胞移植治疗持续性植物状态的可行性及临床效果。
OBJECTIVE: To explore the possibility and clinical effect of bone marrow stromal cells-derived neural stem cell transplantation for treating patients with persistent vegetative state.
研究骨髓间充质干细胞在体外诱导分化为肌源性细胞的可行性。
Rat pancreatic extract induces rat muscle-derived stem cells to differentiate into insulin-secreting cells in vitro;
研究骨髓间充质干细胞在体外诱导分化为肌源性细胞的可行性。
Rat pancreatic extract induces rat muscle-derived stem cells to differentiate into insulin-secreting cells in vitro;
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