通过正交试验探讨了马钱子粉干燥工艺条件。
The dried condition of the powder of Strychnos nux-vomica was studied by orthogonal design.
目的：研究马钱子配伍甘草对马钱子中主要生物碱的影响。
Objective:To study the effects on the alkaloid components in Strychnos nux-vomical L. uncombined and combined with Glycyrrhiza uralensis Fisch.
酶浸法和氯仿法提取马钱子生物总碱的产率分别为：2.85%、1.86%。
The contents of total alkaloids extracted by two methods were 2.85% and 1.86 respectively.
目的通过优化手段筛选最佳处方及工艺，制备马钱子碱长循环脂质体，并评价其质量。
OBJECTIVE to determine optimized prescription and technique for preparing brucine long-circulating liposomes (BLCL) by means of optimization screening, and to evaluate its quality.
目的阐明疏风活络片急性毒性作用的主要组分，以及其他组分对马钱子急性毒性的影响。
Objective to clarify the main component of acute toxic effect in Shufeng Huoluo pills, and the effects of other components from Shufeng Huoluo pills on acute toxic effect of Semen Strychni.
但因其君药马钱子毒性较大，临床常有不良反应报道，从而影响该药的临床安全使用及国际准入。
It has been called in question on clinical safety, even not accepted by international market, due to toxical Semen Strychni as monarch drug which often induce adverse reaction.
结果含马钱子的疏风活络片的主要急性毒性表现为抽搐强直性痉挛，与马钱子急性中毒症状相似。
ResultsAcute toxic manifestations of Shufeng Huoluo pills were twitch, entasia, which resemble acute toxic symptoms of Semen Strychni.
目的评价和比较马钱子碱及其脂质体对移植性肿瘤模型荷瘤小鼠的肿瘤抑制作用和生存时间的影响。
Objective To evaluate and compare the effects of Brucine and Brucine liposome on restraining transplanted tumor growth, prolonging their survival time in mice with transplanted tumor cells .
目的评价和比较马钱子碱及其脂质体对移植性肿瘤模型荷瘤小鼠的肿瘤抑制作用和生存时间的影响。
Objective To evaluate and compare the effects of brucine and its liposome on inhibiting transplanted tumor growth and prolonging their survival time in mice with transplanted tumor cells.
目的： 对马钱子总碱（SSAE）囊泡凝胶和马钱子总碱凝胶进行体外透皮扩散和抗炎作用对比研究。
Objective: Noisome gel and conventional gel of Semen Strychni alkaloids extract (SSAE) were prepared. The comparative studies of transdermal diffusion in vitro and anti-inflammation were performed.
其药物是由下述重量份的原料制 成的：马钱子、细辛、苦参、白藓皮、老龙皮各20克，食醋1000毫升。
The medical infusion is prepared with the following materials based on weight proportion: respectively 20g of nux vomica, asarum, khosam, burning bush peel and lobaria kurokauae, and 1000ml vinegar.
结论江西法及其改良法炮制的马钱子比其砂烫法和油炸法更易降低毒性，使其安全范围增大，从而提高其临床用药的安全性。
Conclusion Semen Strychni and its processed products of Jiangxi methods and innovated methods can lower the toxicity and improve the safety of clinical use.
结论江西法及其改良法炮制的马钱子比其砂烫法和油炸法更易降低毒性，使其安全范围增大，从而提高其临床用药的安全性。
Conclusion Semen Strychni and its processed products of Jiangxi methods and innovated methods can lower the toxicity and improve the safety of clinical use.
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