一期试验:这些首次在人体上进行的试验评估一个新药应该如何给药(口服,注射入血还是肌肉注射),给药间隔和给药的安全剂量。
Phase I trials: These first studies in people evaluate how a new drug should be given (by mouth, injected into the blood, or injected into the muscle), how often, and what dose is safe.
卫生部门官员曾经预测人们或许需要接种两支疫苗,类似于儿童首次接种季节性流感时的剂量。
Health officials had expected two doses might be needed for H1N1 vaccines, as is the case for young children who receive a seasonal influenza shot for the first time.
作者认为这是首次报道案列显示高计量生长激素和糖尿病有关,呼吁那些服用大剂量的人们经常定期检测其血糖值。
The authors believe that this is the first reported case of diabetes associated with the use of high dose growth hormone, and urge anyone taking high doses to regularly check their blood sugar levels.
该药在1999年首次被作为处方药批准使用,而今后需大剂量将该药用于肥胖的药物治疗时仍需持有医师的处方。
The drug, which was originally approved for prescription in 1999, will retain prescription status at higher doses for the medical treatment of obesity.
首次发现在引发剂量增加而导致微球粒径增加时,在增加的趋势中存在“临界点”;③。
Secondly, A critical point was found during the particle size increasing with increasing initiator concentration for the first time.
这个公司说这个结果代表了在这方面的一个重大突破,这是首次用如此低剂量的H5N1抗原产生如此强的免疫反应。
The company says the results represent a significant breakthrough and is the first time such a low dose of H5N1 antigen has been able to stimulate such a level of strong immune response.
而且,要达到这一水平的保护作用,还需要一个典型的流感疫苗的抗原剂量的12倍剂量,注射还分两次进行,第二次注射与首次注射间隔好几个星期。
Reaching even that level of protection required 12 times the dose of antigen delivered by a typical flu shot, and required that the treatment be given in two shots several weeks apart.
年龄在6月至8岁之间的儿童,如果在首次接种时仅接受单个剂量,那么应该在次年接受2倍剂量,随后每年接种单个剂量。
Children aged 6 months to 8 years who received only 1 dose in their first year of vaccination should receive 2 doses in the following year and single annual doses in subsequent years.
存活细胞经二次照射后,SCGE结果和微核发生率结果表明,首次照射剂量与子代二次照射后的损伤程度存在剂量效应关系。
After the survival cells were given second irradiation, both results of SCGE and micronucleus frequency showed that the second damage was correlated with the original irradiation doses.
存活细胞经二次照射后,SCGE结果和微核发生率结果表明,首次照射剂量与子代二次照射后的损伤程度存在剂量效应关系。
After the survival cells were given second irradiation, both results of SCGE and micronucleus frequency showed that the second damage was correlated with the original irradiation doses.
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