模拟抑制剂与靶标分子的结合作用是计算机辅助药物设计的关键部分。
Modeling interaction between inhibitor and target molecule is a key step in CADD.
这种技术可在DNA靶标分子的任意位点进行基因敲除、敲入、点突变等操作,无需使用限制性内切酶和连接酶。
The Red mediated recombination can be used to insert, delete or substitute DNA sequences at any desired position on a target molecule without the need for restriction enzymes or DNA ligases.
该生物学家拥有包括将分子导入活体细胞的纳米注射器、人工骨科材料、结核病靶标治疗和细胞芯片平台等专利。
The biologist holds patents including a cell nanoinjector that introduces molecules into living cells, artificial bone materials, targets for tuberculosis therapy and cell microarray platforms.
该分子可能成为治疗乳腺癌的潜在靶标。
所有这些基因都负责熟知的药品(诸如抗抑郁药、精神抑制药与包括百忧解、舒马曲坦与安理申等在内的止疼片)的分子靶标的编码。
The genes all encode molecular targets of well-known pharmaceuticals, such as antidepressants, antipsychotics and pain relievers including Prozac, Imitrex, and Aricept.
同翅目害虫的抗性机制主要包括代谢抗性和靶标抗性,其中前者在分子水平上多涉及酯酶基因扩增。
The resistance mechanisms of homopteran pests to insecticides included metabolic resistance and target resistance, and the former was mainly involved in esterase gene amplification.
杜戴说:“在片刻之内你可以识别分子机制从而保存记忆,你也可以识别潜在的靶标药物。这项研究主要的受众人群是那些有记忆缺陷的患者。
"The minute you identify a molecular mechanism that is critical for keeping memory going, you identify a potential target for drugs, " he said. "The prime target is people with defective memories.
现对化学基因组学研究的典型方法,以及对基于药物作用靶标的分子设计的影响作一介绍。
This article introduces the typical methods of chemogenomics research and its effect on molecular designing in view of target.
目的在转录组水平全面迅速地了解疾病发生和药物作用的分子机理,以及寻找潜在的治疗靶标。
Objective to get an insight into the molecular mechanisms of diseases development and targeted therapy at the transcriptome level and search for potential therapeutic targets.
用分子细胞生物学、生物化学、遗传学等手段研究肿瘤细胞内的信号传导通路与肿瘤发生机理;筛选肿瘤治疗特异性靶标与新药开发。
Using molecular cell biology, biochemistry, genetics and other approaches to study the signal transduction pathways in cancers and establish tumor targeting strategy for drug development.
作为药物分子的靶标之一,DNA与药物分子的作用可能会引起遗传信息的改变。
As one of possible targets, DNA can be attacked by the molecules of pesticides, which may bring genetic information some changes.
我们相信通过进一步地阐明突触外NMDA受体参与癫痫发生的分子机制,可为癫痫的治疗及预防提供合适的靶标作为参考。
Elucidating the extrasynaptic NMDA receptors-mediated molecular mechanisms in epileptogenesis will provide a potential cue for the effective treatment of epilepsy.
网络靶标概念指的是将病证生物分子网络当作靶标,由此设计和预测最佳的药物干预方式。
The network target treats a disease-specific biomolecular network as a target to help design and predict the best possible treatments.
然后进行U 251细胞系中肿瘤干细胞的凋亡机制的探讨,从而为脑胶质瘤的防治及肿瘤疫苗的研制提供新的策略和分子靶标。
Then, based on U251 cell lines tumor stem cell apoptosis mechanism will be discussed. Accordingly provide new strategies for the therapy in glioma.
然后进行U 251细胞系中肿瘤干细胞的凋亡机制的探讨,从而为脑胶质瘤的防治及肿瘤疫苗的研制提供新的策略和分子靶标。
Then, based on U251 cell lines tumor stem cell apoptosis mechanism will be discussed. Accordingly provide new strategies for the therapy in glioma.
应用推荐