SLN可以作为治疗肝脏疾病药物的良好肝靶向载体。
SLN is a good liver-targeted drug delivery system for the drug of treating liver disease.
肿瘤靶向治疗中治疗靶点、靶向载体和效应分子的选择是关键。
In the research of tumor targeting therapy, how to select therapy target, tumor-homing vehicles and antitumor element is the most important.
结论:肝癌特异性多柔比星免疫磷脂纳米粒,有可能成为一种新的药物靶向载体系统。
Conclusion: Doxorubicin phospholipid nanoparticle is able to become a new drug targeting carrier system.
再以固载组氨酸的磁性纳米球作为磁靶向载体,开展普通羰基铼的初步模拟标记实验。
Using the magnetic nanospheres immobilized with histidine as magnetic targeted carrier, the simulative labeling experiment of them with tri-carbonyl rhenium was primarily developed.
实验结果表明N-乳糖酰壳聚糖是ASGPR的特异性配基,对肝细胞具有“主动”靶向作用,可作为肝靶向载体。
The results indicated that N-Lactosyl-Chitosan was a good ligand for ASGPR, and could be used as hepatic targeting carrier of antitumor drugs.
目的选择一种最佳铁碳复合磁性材料作为药物载体,用于肿瘤的磁靶向治疗。
Objective To select the best magnetic iron-carbon composite microparticles as a drug carrier in magnetically targeted therapy of tumor.
目的探讨乙型肝炎病毒(HBV)作为肝靶向性基因治疗载体的可能性。
Objective To evaluate the possibility of hepatitis B virus (HBV) as a vector in liver-targeting gene therapy.
脂质体作为溶栓药物载体,经RGDS修饰后,具有较好的靶向性抗血栓作用。
The results show liposomes as the carrier of medicine has better target anti-thrombus effect after RGDS modifies it.
目的:构建基质金属蛋白酶9靶向的RNA干扰质粒载体,观察其对小鼠巨噬细胞基质金属蛋白酶9基因表达的沉默作用。
AIM: to construct plasmid vector of RNA interference specific for matrix metalloproteinases (MMP) -9 and observe the silencing effect on gene expression of MMP-9 in macrophage of mice.
载体的靶向策略很多,载体重靶向就是其中重要的一种。
Vector retargeting is one of the important strategies on viral vector targeting.
目的制备磁响应性强、粒径小且分布均匀的磁性纳米微粒,为消化道恶性肿瘤的磁控靶向治疗提供一种新型载体。
Objective To improve the method of synthesizing magnetic particles, which have good magnetic property and small size, to be used in tumor target therapy.
有效并且安全的靶向性载体是基因治疗能否成功的关键。
Effective and secure targeted vector is the key of the gene therapy succeed or not.
理想的纳米粒载体应有特异靶向性、药物释放可控性,无毒性以及可生物降解等。
The perfect nanoparticle vectors should be specific-targeting, controlled release, nontoxicity? biodegradation, and so on.
肿瘤靶向基因治疗的主要目的是用靶向性的载体将治疗基因靶向传递到肿瘤细胞。
A major goal of tumor-targeting gene therapy is to transfer genes efficiently to tumor cells by targeted vectors.
结论:采用磁流体作为药物的载体,在外磁场作用下可实现靶向控制,提高药物在靶部位的聚集浓度。
Conclusion: Ferrofluids as drug carriers can enhance drug concentration in the target with the aid of magnetic field.
目的通过研究不同相对分子质量n -琥珀酰壳聚糖与肿瘤细胞的亲和性,筛选出最佳靶向制剂载体。
OBJECTIVE to investigate the affinity of N-succinyl-chitosan samples to cancer cells, and select the best one as the drug targeting carrier.
本发明公开了一种叶酸受体靶向脂质体药物载体及其制备方法和应用。
The present invention discloses one kind of folic acid acceptor targeting liposome as medicine carrier and its preparation process and application.
方法:分析有关文献资料,对淋巴靶向给药系统的载体材料及其制剂的研究与应用等进行了论述。
METHODS:On the basis of relate literatures, we discussed drug carriers and preparation about lymph targeted drug delivery system (TDDS).
本文就近年来靶向给药系统作为药物载体的研究及其在临床治疗中的应用进行综述。
The Paper reviews the application and progress of targeted drugs delivery system as drug carriers in clinical therapy.
病毒载体的靶向性问题是肿瘤基因治疗中的重要研究热点,靶向病毒载体是提高肿瘤基因治疗安全性和有效性的重要途径。
Vector tropism is a research hot spot in cancer gene therapy, and targeted viral vectors play a key role in the enhancement of safety and efficiency in cancer gene therapy.
通过大量文献,从靶向治疗设计模式、靶向制剂的分类、抗癌靶向药物载体及影响药物靶向性的因素等方面进行探讨。
The models of drug targeting, the categories of drug targeting, the targeted drug carriers, and the factors that influence the effect of targeting are introuduced through domestic literatures.
HBV靶向核糖核酸酶真核表达载体的构建及其在2.2.15细胞内的表达。
Construction of HBV targeted ribonuclease and its expression in 2.2.15 cell line.
目的采用新型壳聚糖载体研究去甲斑蝥素的双重肝靶向制剂。
OBJECTIVE to investigate a dual hepatocyte-targeting preparation of norcantharidin with model chitosan carrier.
本发明具有作为乳腺癌靶向性基因治疗的特异性载体的潜在临床应用价值。
The invention as a specificity carrier of the mammary cancer-targeting genetic therapy has potential clinic application value.
生物可降解型高分子载体控制释放药物和生物可降解型高分子载体靶向药物是近年来高分子药物研究的重点。
Biodegradable macromolecule carried controlled drug releasing and biodegradable macromolecule carried targeted drug delivery are the focus of recent investigation in macromolecular medicine.
温敏在体凝胶作为一种智能水凝胶,可用作药物缓、控释和靶向输送的有效载体。
Temperature-sensitive in situ gel, a kind of smart hydrogel, could be used as a good carrier for sustained, controlled and targeting drug release.
多糖能被结肠内的菌群降解,而被用作结肠靶向给药的载体。
Polysaccharides are used as colon-specific drug delivery carriers because they can be degraded by enzymes produced by colon bacteria.
免疫毒素是近年来新兴的一种特异性靶向治疗药物,由毒素蛋白和载体两部分构成。
Immunotoxin is a novel class of targeted agents in recent years, which is composed of toxin fragment and antibody or cytokine.
综述了淀粉的结构、消化特性、影响淀粉消化特性的因素及其在口服结肠靶向药物控释载体中的应用前景。
This article provides a review of starch structure, digestibility and its influencing factors and the application outlook of starch-based carrier for oral colon-specific drug delivery system.
综述了淀粉的结构、消化特性、影响淀粉消化特性的因素及其在口服结肠靶向药物控释载体中的应用前景。
This article provides a review of starch structure, digestibility and its influencing factors and the application outlook of starch-based carrier for oral colon-specific drug delivery system.
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