每增加一例人间病例增强了该病毒通过适应性突变或重组提高其可传播性的机会。
Each additional human case increases opportunities for the virus to improve its transmissibility, through either adaptive mutation or reassortment.
所有八个基因片断的排序未发现证据表明与人或猪的流感病毒发生基因重组，也无证据表明发生显著突变。
Sequencing of all eight gene segments found no evidence of genetic reassortment with human or pig influenza viruses and no evidence of significant mutations.
而一旦细胞的抗癌防御系统被摧毁，遗传混乱就会随之而来，于是又进一步加剧了基因突变的程度，而且染色体中的DNA将产生大规模重组。
Once the cell’s anticancer defenses are destroyed, genetic mayhem ensues, with further mutations and wholesale rearrangements of DNA in the chromosomes.
当适应度函数和突变、重组及水平基因转移率已知时，该项新的数学上的结果可以使这一机制运算化。
The new mathematical results allow calculation of this mechanism when the fitness function and the mutation, recombination and horizontal gene transfer rates are known.
序列排比结果说明在淀粉酶基因的趋异进化过程中，基因突变和遗传重组都曾起过作用。
Comparison of two DNA sequences suggested that both gene mutation and genetic recombination were involved in the divergent evolution process.
这样的大群体有利于检出稀有的突变或重组子。
These large populations facilitate the detection of rare mutational or recombinational events.
多种因素可以引起DNA损伤而最终导致基因产生错义突变、缺失或错误重组。
DNA damage caused by many factors may lead to missense mutation, deletion or illegal recombination.
从存活率、生存状态和小肠组织病理切片等方面分析重组人KGF-2突变体的防治效果。
The effect of recombinant human KGF-2 mutant can be analyzed through the survival rate, living status and pathological tissue slice of small intestine.
给予正确的版本作为模板，经检测，在断裂位点发生的重组事件中，11%的细胞用一个一个突变基因交换了一个正确的基因。
Given the correct copy as a template, the recombination event occurred at the break site and 11 percent of the cells tested had traded one copy of the mutant gene for the correct version.
结果突变基因重组表达质粒构建正确；
Results The recombinant plasmid with mutant gene was constructed correctly.
本发明还涉及人源化改造的基因突变技 术和去除GFP的腺病毒转移载体及去除GFP的同源重组腺病毒载体。
The invention also relates to a human reforming gene mutation technique, adenovirus transition carrier removing GFP and homologous recombinant adenovirus carrier.
将含突变基因的重组质粒转化大肠杆菌菌株bl2 1 (DE3)，经IPTG诱导表达获得的目的蛋白质均以可溶形式存在。
The recombinant plasmids containing mutant genes were transformed into the Escherichia coli strain BL21 (DE3), and the expressed proteins were found to be water soluble after the induction of IPTG.
目的构建人鸟氨酸脱羧酶抗酶(OAZ)突变基因，重组至原核表达载体中并表达出重组蛋白。
Objective To clone human ornithine decarboxylase antizyme (OAZ) mutation gene and express its recombinant protein.
许多研究小组利用整基因随机突变形成和重组方法，已成功的进行了酶的定向进化。
Many research groups successfully rely on whole-gene random mutagenesis and recombination approaches for the directed evolution of enzymes.
将筛选的抗体模拟肽与TSST - 1突变体基因融合或化学耦联，构建重组表达质粒。
Through crosslinking the specific peptide and the gene of TSST-1, we got the recombination plasmid.
动态的基因突变和基因重组被认为是流感病毒A的致病性和宿主趋向性改变的关键因子。
Dynamic gene mutation and the reassortment of genes have been considered as the key factors responsible for influenza a virus virulence and host tropism change.
方法将小鼠分为正常组、模型组、重组KGF - 2突变体防治组和安多霖防治组。
MethodsThe Mice were divided into normal group, model group and other two groups administrated by recombinant human KGF-2 mutant or Anduolin.
HIV病毒是人类最大遗传变异的病原体，具高复制性，高突变性，高重组性。
HIV virus is the largest genetic variation in human pathogens, with a high reproduction, high mutation, the reorganization of the high.
方法使用人工定点突变多聚腺苷酸化信号的小鼠逆转录病毒载体，应用PA317病毒包装细胞获得多聚腺苷酸信号缺陷的重组逆转录病毒；
Methods The polyadenylation signal-deficient retrovirus vector mutated by PCR site-directed mutagenesis was used to make polyadenylation signal-deficient retroviruses by PA317 packaging cells.
病理切片观察结果显示，重组人KGF-2突变体给药能够促进小肠隐窝细胞的增生，加快受损肠黏膜上皮的修复。
The results of pathological tissue slice showed that administration of the KGF-2 mutant could promote the proliferation of intestinal crypt cells, and restore the injured intestinal mucosa.
用本发明方法制备的猴金属硫蛋白I的六个突变体蛋白，产量与纯度均与野生型重组蛋白类似。
Using the said method to prepare 6 mutant proteins of monkey metallothionein I can obtain yield and purity similar to that in wild recombinant protein.
用本发明方法制备的猴金属硫蛋白I的六个突变体蛋白，产量与纯度均与野生型重组蛋白类似。
Using the said method to prepare 6 mutant proteins of monkey metallothionein I can obtain yield and purity similar to that in wild recombinant protein.
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