目的考察醇质体凝胶作为炔雌醇透皮给药载体的可行性。
OBJECTIVE To investigate the feasibility of ethosome gel as transdermal carries of ethinyl estradiol (EE).
透皮吸收制剂,特别是透皮给药系统是近年来药剂研究的重要课题之一。
The study on percutaneous absorption preparations, especially transdermal therapeutic systems is one of the important topics on medications.
方法:采用麻黄碱贴膏,比较在体透皮给药对豚鼠整体平喘作用的影响。
METHODS:The gelatinizer made from ephedrine was taken as the treatment to carry research for antiasthmatic effect and compared the difference between therapeatic and control drug.
结论采用均匀设计法优选的配方组成符合骨架控释型透皮给药系统的要求。
Conclusion the prescription composition optimized by uniform design meets the requirement of skeleton-controlled transdermal delivery system.
目的:介绍近年来国内外透皮给药的研究进展,以促进透皮给药系统的开发。
Objective:To promote development of transdermal drug delivery system and present the internal and external advancement of recent years.
选择壳聚糖作为透皮给药系统的控释材料,并对壳聚糖的成膜条件进行了研究。
Chitosan was chosen as the controlling materials for the transdermal drug delivery system, and the conditions of preparing chitosan membranes were researched.
结果提示,这种聚乙烯醇凝胶可望作为药物透皮给药系统的一种新的良好载体。
The results show that the PVA gel may be a fine carrier for transdermal therapeutic system.
这样,研制适宜的辅料如:载体、促渗材料和骨架材料等成为了研制透皮给药系统的重心。
Therefore, the key problems in the TDDS are the development of proper auxiliary materials such as carriers, enhancers and bone materials.
结论:瞬间脉冲电场能够显著提高水凝胶贴剂的透皮给药效果,两者结合将成为一种新型透皮给药技术。
These results suggest that cataplasma to combine with electroporation may be an efficient alternative for transdermal drug delivery of hydrophilic molecules.
良肤软膏是由牡丹皮、白鲜皮、薄荷脑三味药的相关有效成分提取物制备而成的用于治疗皮肤瘙痒的透皮给药制剂。
Liangfu Ointment, which is prepared from effective components of three Chinese herbs, is a transdermal drug delivery system for the treatment of pruritus.
本文重点介绍了一些新的给药途径和给药系统,例如鼻腔、颊等给药途径以及黏膜给药系统、透皮给药系统、缓控释技术等给药系统的进展。
The effect of buccal mucosa in different regions on penetration and absorption of drugs, various and quality evaluation methods of buccal mucosa drug delivery system are introduced.
结论:1,2 -丙二醇,月桂氮卓芯酮—胰岛素传递体经皮给药系统可进一步提高胰岛素传递体的透皮吸收效率,降低血糖。
CONCLUSION Transfersulin system with azone and 1, 2-propanediol can improve the penetration efficiency on mice skin and eliminate the blood glucose.
目的由于皮肤的屏障作用,经皮给药系统的应用受到限制,促透方法的研究成为焦点。
Because of the barrier of skin, the application of transdermal delivery system is limited. It is very important to study enhancement methods of drug percutaneous absorption.
目的由于皮肤的屏障作用,经皮给药系统的应用受到限制,促透方法的研究成为焦点。
Because of the barrier of skin, the application of transdermal delivery system is limited. It is very important to study enhancement methods of drug percutaneous absorption.
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