目的观察雌激素对骨关节炎（OA） 模型软骨基质蛋白多糖变化的影响，探讨外源性雌激素治疗OA的作用机理。

Objective To observe the effects of ectogenetic estrogen on changes of proteoglycan (PG) in articular cartilage matrix of osteoarthritis(OA) and to explore the treatment of ectogenetic estrogen on OA.

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目的：探讨我国多发性骨骺发育不良患者中软骨寡聚物基质蛋白（COMP）基因的突变情况。

Objective: Our aim was to study the characteristics of mutation of cartilage oligomeric matrix protein (COMP) gene in Chinese patients with multiple epiphyseal dysplasia( MED).

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牙本质基质蛋白(DMP)- 1是骨、软骨、釉质、牙骨质和牙本质生物矿化所必需的一种酸性非胶原蛋白。

Dentin matrix protein (DMP) -1 is an acidic non-collagenous protein that is necessary for the proper biomineralization of bone, cartilage, cementum, dentin and enamel.

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牙本质基质蛋白(DMP)- 1是骨、软骨、釉质、牙骨质和牙本质生物矿化所必需的一种酸性非胶原蛋白。

Dentin matrix protein (DMP) -1 is an acidic non-collagenous protein that is necessary for the proper biomineralization of bone, cartilage, cementum, dentin and enamel.

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