目的探讨乳腺癌转移抑制因子(BRMS1)在乳腺癌中的表达及其与雌激素受体(ER)、孕激素受体(PR)的相关性。
Objective to study breast cancer metastasis suppressor 1 (BRMS1) gene expression in breast cancer and its relationship with estrogen receptor (er) and progesterone receptor (pr).
目的研究抗血管内皮生长因子(VEGF)对胃癌生长和转移的抑制作用。
Objective to study the inhibiting effect of anti vascular endothelial growth factor (VEGF) on the growth and metastasis of gastric cancer.
目的研究血管生成抑制因子su 5416对结肠癌生长和转移的抑制作用。
Objective to study the effects of angiogenesis inhibitor SU5416on the growth and metastasis of colon cancer in vivo.
例如，委员会使用的关于单克隆抗体西妥昔单抗和帕尼单抗(它们抑制转移性结直肠癌的表皮生长因子受体egfr)的数据。
For example, the Panel used data for the monoclonal antibodies cetuximab and panitumumab, which inhibit the EGF receptor (EGFR) in metastatic colorectal cancer.
目的：探讨白血病抑制因子受体（LIFR）与人涎腺腺样囊性癌转移的相关性。
Objective:To study the expression of Leukemia inhibitory factor receptor (LIFR) in human salivary gland adenoid cystic carcinoma cell lines with different metastatic potential.
血管形成是实体肿瘤增殖和转移的关键步骤，这一过程依赖于内源性刺激因子和抑制因子之间的平衡。
Angiogenesis is the key step in tumors proliferation and metastasis, which depends on the net balance between endogenous stimulators and inhibitors.
DNA甲基化由DNA甲基转移酶催化，在多种调节因子的参与下，与组蛋白修饰相互作用，抑制基因转录，导致基因沉默。
DNA methylation catalyzed by DNA methyltransferases interacts with histone modification to inhibit gene transcription, induce gene silencing at the participation of many regulators.
另外，表面半乳糖基转移酶通过调节表皮生长因子受体信号传导能力向胞内传递生长抑制信号，在细胞增殖控制中起重要作用。
Surface GalTase also delivers a growth inhibitory signal by modulating the ability of the EGF receptor to transduce EGF dependent signals, and plays an important role during cell growth.
TGF配体虽然在早期肿瘤中作为肿瘤抑制基因发挥作用，但其在进展期肿瘤中却变成有效的促转移因子。
TGF ligands act as tumor suppressors in early stage tumors but are paradoxically diverted into potent prometastatic factors in advanced cancers.
肿瘤血管生成是肿瘤生长转移的关键步骤，是促血管生成因子和抑制因子作用失衡的结果。
Tumor angiogenesis, resulting from the imbalance of angiogenic cytokines and angiogenesis inhibitors, is crucial for tumor growth and metastasis.
目的研究壳寡糖对小鼠肿瘤生长和转移的抑制作用以及壳寡糖对培养的巨噬细胞相关的细胞因子表达的影响。
Objective to study the influence of oligochitosan in inhibiting growth and metastasis of tumor in rats, and in expression of cytokines associated with macrophage.
结果：抗乙肝转移因子与普通转移因子相比，使未粘附白细胞显著增多（P< 0 .0 1） ，未粘附抑制指数达82 %。
Results:The ratio of non-adhesion leucocyte increased significant ly when compared with the normal TF group-(P-<0.01), and the non-adhesion inhibition index(NAI) achieved 82%.
结论壳寡糖具有良好抑制肿瘤生长和转移的作用。壳寡糖可增强巨噬细胞相关的细胞因子表达。
Conclusion Oligochitosan can inhibit growth and metastasis of tumor, and enhance expression of cytokines associated with macrophage.
结论壳寡糖具有良好抑制肿瘤生长和转移的作用。壳寡糖可增强巨噬细胞相关的细胞因子表达。
Conclusion Oligochitosan can inhibit growth and metastasis of tumor, and enhance expression of cytokines associated with macrophage.
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