同时分析SFRP2基因超甲基化与临床病理特征的关系。

And the relationship between hypermethylation of SFRP2 gene and clinicopathological features were analyzed.

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目的：研究分泌型卷曲相关蛋白2（SFRP2）基因启动子超甲基化与大肠癌的关系。

Objective:To investigate the function of promoter hypermethylation of secreted frizzled-related protein 2(SFRP2) gene in colorectal cancer.

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但这种机制尚不完善：“如果你审视肿瘤，它们往往具备整体低甲基化，但某些基因却超甲基化，”萨皮恩扎说。

But the mechanism isn't perfect: "If you look at tumors, they tend to have hypomethylation overall, but hypermethylation in some genes," Sapienza says.

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但这种机制尚不完善：“如果你审视肿瘤，它们往往具备整体低甲基化，但某些基因却超甲基化，”萨皮恩扎说。

But the mechanism isn't perfect: "If you look at tumors, they tend to have hypomethylation overall, but hypermethylation in some genes," Sapienza says.

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