以肝素钠为原料,经成盐、酯化、解聚和纯化得到依诺肝素钠。
Enoxaparin sodium was prepared from heparin sodium via salinization, esterification, depolymerization and purification.
那屈肝素也有相关研究,但主要是关于依诺肝素的研究比较多。
Nadroparin has been studied as well, but the main results have been achieved with enoxaparin.
并且同时应用氯吡格雷和依诺肝素的患者心血管事件的发生率最低。
The rates of adverse cardiovascular events were lowest in patients treated with both clopidogrel and enoxaparin, the investigators report.
这导致与依诺肝素相比,包括死亡、心梗、卒中和出血等方面的疗效更好。
This led to a better efficacy in terms of death, MI, stroke, and bleeding versus enoxaparin.
不管是否服用氯吡格雷,依诺肝素都较普通肝素具有更明显的安全性和有效性。
The significantly improved safety and efficacy profile of enoxaparin versus unfractionated heparin was maintained regardless of clopidogrel administration.
Danchin教授: 现在有多种低分子肝素,在治疗ACS方面依诺肝素是研究最多的一种。
Prof. Nicolas Danchin: There are many LMWHs and in the context of ACS it is essentially enoxaparin which has been studied in the greatest number of trials.
研究了影响酯化率与成环率的主要因素,控制合适的酯化、解聚和纯化条件,得到的依诺肝素钠成品符合欧洲药典标准。
Major factors that affected the degree of esterification and 1,6-anhydro ring formation were studied to produce the title compound which met the European Pharmacopoeia standard.
目的探讨在择期经皮冠状动脉介入(PCI)治疗中静脉应用伊诺肝素的有效性和安全性以及与普通肝素对比的疗效差别。
Objective To investigate the effectiveness and safety of intravenous enoxaparin application in PCI and its therapeutic effect compared with unfractionated heparin.
他们建议:由于使用依诺肝素和阿司匹林对母亲和胎儿具有最小限度的风险,对于经历过三次甚至更多怀孕失败的妇女,上述任意一种形式的治疗都应该被考虑。
"In view of the minimal risks of enoxaparin and aspirin to the mother and fetus," they recommend that "either form of treatment should be considered in women after three or more pregnancy losses."
他们建议:由于使用依诺肝素和阿司匹林对母亲和胎儿具有最小限度的风险,对于经历过三次甚至更多怀孕失败的妇女,上述任意一种形式的治疗都应该被考虑。
"In view of the minimal risks of enoxaparin and aspirin to the mother and fetus," they recommend that "either form of treatment should be considered in women after three or more pregnancy losses."
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