洛非西定的血浆蛋白结合率约为38%。
用透析法测定药物的狗血浆蛋白结合率。
The serum protein binding rate in dogs was determined by dialysis method.
最后用三氯醋酸法测定其血浆蛋白结合率。
Finally, the binding rate of plasma protein was determined by trichloroacetic acid precipitation.
目的:测定盐酸去氢骆驼蓬碱的血浆蛋白结合率。
OBJECTIVE To study the plasma protein binding rate of harmine hydrochloride.
蛋白结合率低。
结果表明人与大鼠药代动力学参数的差异不是由蛋白结合率的差异所导致。
According to our results, it was concluded that the PK parameters differences between human and rat were not due to plasma protein binding.
方法:用分光光度法测定cyp450含量,用平衡透析法测定蛋白结合率。
Methods: the binding rate of DCPB to plasma protein was determined by equilibrium dialysis method, and the content of CYP450 was assayed by differential spectrum method.
结果未加及加入氢氯噻嗪后的替米沙坦的蛋白结合率分别为93 8%和94 1%。
Results The protein-binding rate of telmisartan to BSA was 93.8% and 94.1% respectively when incubated without and with hydrochlorothiazide.
结论:该方法简便易行,能够有效测定硫酸阿托品和氢溴酸东莨菪碱蛋白结合率及蛋白结合参数。
Conclusion: the method was simple and convenient. The protein binding rates and protein binding parameters of atropine sulfate and scopolamine hydrobromide were determined with the method effectively.
方法:采用超滤法结合高效液相色谱法测出游离药物浓度,比较未加和加入甲硝唑后头孢噻肟钠的蛋白结合率。
Method: Ultrafiltration and HPLC were employed to measure the conc. of free drug. The difference in protein-binding between cefotaxime alone and together with metronidazole was examined.
药物对映体结构特异性对局麻药药代动力学的各个过程都有着很大影响,包括药物的吸收、蛋白结合率、代谢等。
The enantiomer-specific structure of local anaesthetics has large impact on the pharmacokinetic process of these drugs, including absorption, protein-binding ratio, metabolism, and so on.
目的应用人工神经网络方法对6 1种抗生素进行药物分子结构和药物血浆蛋白结合率的定量结构-药物动力学关系的研究(QSPR)。
OBJECTIVE To study and demonstrate the application of neural network to research the quantitative structure-pharmacokinetic relationship(QSPR)of 61 kinds of antimicrobial agents.
表观分布容积为0.15~0.31/kg、蛋白质结合率为30~4C%。
The apparent volume of distribution is 0.15~0.31/kg and protein binding 30~40%.
近年来发现高迁移率族蛋白B1(HMGB1)这一传统DNA结合蛋白是强大的致炎细胞因子。
Recently, the traditional DNA-binding protein HMGB1 was discovered as a potent proinflammatory cytokine.
目的:筛选高迁移率族蛋白b 1 (HMGB1)启动子结合蛋白。
AIM: to screen the binding proteins to HMGB1 promoter by phage display technique.
目的:筛选高迁移率族蛋白b 1 (HMGB1)启动子结合蛋白。
AIM: to screen the binding proteins to HMGB1 promoter by phage display technique.
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