目的观测甲氨蝶呤植入剂的高温融熔生产工艺对药物结构的影响。
Objective To examine and analyse the structural change of drugs in the implants produced by high-temperature fusible technics.
方法：以双酮为原料，结合双烯孕腈的药物结构特点对双炔失碳酯进行化学结构改造。
Methods: Referring to dienogest's construction features, we reconstructed anordrin be- ginning with diketone.
本文综述了近年来该类药物结构修饰和构效关系的研究进展，为进一步进行新药研究提供线索。
In this paper, their structural modification and structure-activity relationship are reviewed in order to give some clues for the further research.
本文介绍了热分热方法在测定药物纯度判断药物的熔化特性。研究药物结构及剂型选择，测定含水量变化等的应用。
This paper has introduced the thermal analysis methods applied in the determination and study of the purity, melting property, changes of water contents, structures and preparation of drugs.
最近的研究还发现，斑马鱼不仅用于新药筛选，还可用于药物结构的优化。本文重点介绍斑马鱼在新药发现中的应用。
This review summarizes recent progress in drug discovery including identification and validation of novel drug targets, and screening for new therapeutic compounds.
解决压迫穷人的不平等、种族主义和其他形式的“结构性暴力”与推广药物一样重要。
Tackling the inequality, racism and other forms of "structural violence" which oppress the poor is as critical as extending the drugs.
可用于合成各种具芳基胺醇类结构的手性药物。
It can be oriented to produce levo-aromatic and dextro-aromatic alcohols.
药物具有一个完全不同的成本结构。
用药物靶子的三维结构作为起点进行新药分子的系统化设计。
The systematic design of new drug molecules using the three-dimensional structure of the drug target as a starting point.
一种可能的结果是合成一类能够通过口服而且其结构不会被消化液中所含有的酸性物质所破坏的新型药物。
One outcome might be a new class of drugs that can be swallowed without being destroyed by the acids in the digestive tract.
而弄清楚这些分子的结构有助于科学家们去研究那些由畸形蛋白质引起的疾病，并找出更好的药物靶点。
Figuring out such structures could help scientists learn more about diseases caused by malformed proteins and identify better drug targets.
佛罗里达大学的Chauhan博士说：“这些维生素结构类似‘纳米砖块’，药物分子不能够通过维生素e，只能够绕过去。”
Dr Chauhan, of the University of Florida, said: 'These vitamin structures are like "nano-bricks". The drug molecules can't go through the vitamin e, they must go round it.
“许多药物分子是手性的，并且两种镜象结构在药理上（pharmalogically）有所区别，对人体的作用是不同的”，科恩说。
"Many drug molecules are chiral and the two mirror images are pharmalogically different and do not have same interactions with the body," says Cohen.
没有提供药物的基础结构，世界上所有的捐赠药物均不能发挥作用。
All the donated drugs in the world won't do any good without an infrastructure for their delivery.
好的蛋白结构分辨率对于对于很多应用都是非常重要的，包括但不限于虚拟筛选药物靶点与对接程序和蛋白质设计。
Better resolution is important for a number of applications, including but not limited to virtual screening of drug targets with docking procedures and protein design.
合理化药物设计利用靶分子和其结合分子的高分辩率结构。
Rational drug design (also known as structure-based drug design) uses the high-resolution (atomic) structure of the target molecule, and of molecules that bind to it.
某种药物是否侵犯了一个公司的专利，通过检验其分子结构就一目了然了。
A me-too drug that is believed to violate a firm's patent is either based on the same molecule or not.
并不是所有物种都伴随有衰老的现象。一些研究表明通过使用某些药物或者改善饮食结构可以减速生物的新陈代谢以及改变基本的衰老过程，以此来帮助我们延年益寿。
Not every species ages, and some research suggests that drugs or changes in diet may slow metabolism or alter basic aging processes so that we can live longer.
能够影响蛋白的结构和功能的模型对于评估和预见药物的作用是很有用的。
Models that simulate effects of perturbing protein structure and function are therefore highly relevant to assessing and predicting drug actions.
“这些口袋结构可以被塑造成适合一定的细胞特征，”Shih说，“这样就可以用来设计针对单一类型细胞的药物传输或诊断分子。”
Those pockets could be molded to fit specific cellular features, said Shih, allowing for the design of drug-delivering or diagnostic molecules targeted at a single type of cell.
但是不管时间有多长，任何药物的结构改变都会改变他们对靶点的作用能力。
Any alteration of a drug's structure, however, will change its ability to interact with its target, regardless of the length of time involved.
主要包括改变饮食结构，自我调节缓解生活压力，以及通过药物的方式治疗便秘或腹泻症状。
These include diet changes, stress management, and medications to treat diarrhea or constipation.
相反，象赫赛汀等药物作用靶点在细胞外，而且是大分子结构。
In contrast, older drugs such as Herceptin have larger molecular structures that target the outside of the cell.
现在，现代科学研究发现药物精确的分子结构，从而优质的药物正在向更高级的形式进化。
Now, modern science reveals precise molecular structures of drugs, and thereby superior drugs are evolving into more advanced forms.
例如，他在编辑评论中说，适度的改变饮食结构比药物、入侵程序或者设备更加低风险、低成本和易于接收。
For instance, he notes in his editorial that modest dietary changes are less risky, less costly, and more accessible than drugs, invasive procedures, or devices.
这些结果可能为药物分子设计和相关酶的结构分析提供了某些信息和思路。
These results may provide valuable information and thinking on the drug molecular design and related enzymic structure analysis.
这些结果可能为药物分子设计和相关酶的结构分析提供了某些信息和思路。
These results may provide valuable information and thinking on the drug molecular design and related enzymic structure analysis.
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