五个非洲国家目前正在开展候选艾滋病毒疫苗的一期和二期临床试验:博茨瓦纳、肯尼亚、卢旺达、南非、乌干达,坦桑尼亚很快也将介入。
Five African countries are currently conducting phase I and phase II clinical trials of candidate HIV vaccines: Botswana, Kenya, Rwanda, South Africa, Uganda, soon to be joined by Tanzania.
美军艾滋病毒研究项目(mhrp)的研究人员在上个月宣布试验取得成功。
Last month's announcement of success (PDF) was made by researchers from the US Military HIV research Program (MHRP).
伊里诺斯州西北大学的罗伯特·墨菲正在主导这样的一次临床试验,他说病人在服用一剂量的白细胞介素- 7后,其血液中确实可发现被重新唤醒的艾滋病毒影像。
Robert Murphy of Northwestern University, in Illinois, who is leading one of the clinical trials, says blips of reawakened virus can indeed be seen in patients' blood after a dose of interleukin-7.
试验中一共招募了16,400多个泰国的男性和女性被,他们年纪在18至30岁间,并且都没有感染艾滋病毒。他们被随机分配接受疫苗或安慰剂。
More than 16, 400 Thai men and women aged 18 to 30 who did not have HIV were recruited and randomly assigned to receive the vaccine or a placebo.
到了试验结束时,只有125人感染了艾滋病毒。
By the end of the trial only 125 people had become infected with HIV.
艾滋病毒攻击免疫细胞,在实验室试验中,病毒在愈后皮肤组织的繁殖速度,要比其他皮肤组织快3到5倍。
HIV targets immune cells and in laboratory tests the virus reproduced three to five times faster in tissue from the healed sites as in tissue from other areas.
与此同时,该研究团队正在继续进行更多的研究和临床试验,以便改善这种治疗方法;这样患者就能接受更多的转基因干细胞,以便他们能够产生对艾滋病毒更大的耐受性。
Meanwhile the team is continuing with more research and clinical trials to improve the therapy so patients receive more genetically modified stem cells so they can develop greater resistance to HIV.
科学家承认,最近在泰国进行的一种艾滋病毒疫苗试验,效果没有达到预期的设想,但他们表示,试验仍然可以为将来进一步的研究提供有价值的参考。
Scientists acknowledged that an HIV vaccine recently tested in Thailand may be less effective than they originally suggested, but said it still provided valuable leads for further research.
科学家承认,最近在泰国进行的一种艾滋病毒疫苗试验,效果没有达到预期的设想,但他们表示,试验仍然可以为将来进一步的研究提供有价值的参考。
Scientists acknowledged that an HIV vaccine recently tested in Thailand may be less effective than they originally suggested, but said it still provided valuable leads for further research.
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