异常的超变和异常的致癌基因 BCL-6与淋巴瘤的发生具有相关性。
Aberrant somatic hypermutation and deregulation of the oncogene BCL-6 are associated with lymphomagenesis.
一部分原因在于，癌症的出现往往要经历数十年，因此，要想揭示其导致癌症发生率的增加，必须要对实验对象进行长时间的跟踪。
Part of the problem is that cancer can take decades to appear, so only a lengthy follow-up will expose an increase in its incidence.
但是由于研究显示，这种疗法更易导致癌症，心血管疾病等的发生，不少女性不得不停止治疗，所以新的研究目标在于单独使用睾酮，而不再结合雌性激素的疗法。
Many women have stopped the combination therapy because of studies linking it to cancer, cardiovascular and other risks, so the new study looked at women given testosterone without estrogen.
死亡率增加的原因可能是由于雌激素刺激新血管生长——导致癌症发生或扩散。
The reason for the increased mortality could be oestrogen stimulating the growth of new blood vessels - which can cause the cancer to grow and spread.
科学家表示手机不会导致癌症，因为近二十年来脑瘤发生的几率并未上升。
Scientists have concluded that using mobile phones does not lead to cancer as the incidence of brain tumours have not risen in the last two decades.
Lancet杂志阐述说这个研究提供了证据说明极热的液体会引起咽喉上皮层膜组织的损伤并导致癌症，即使实际上这个过程是如何发生的仍旧未能清楚。
The Lancet says the study backed evidence that scorching fluids may cause damage to the throat's epithelial lining and lead to cancer, although exactly how this happens remains unclear.
茶垢中含有镉、铅、汞、砷等多种有害金属和某些致癌物质，如亚硝酸盐等，可导致肾脏、肝脏、胃肠等器官发生病变。
Tea scale contain cadmium, lead, mercury, arsenic and other harmful metals and some carcinogens, such as nitrite, can cause kidney, liver, gastrointestinal lesions occur in other organs.
室内物品表面上烟草烟雾烟残留物当与室内空气中的化学成分发生反时应会形成致癌物。
Residues of cigarette smoke deposited on indoor surfaces can turn carcinogenic when they react with airborne chemicals.
作者们认为针对这种情况由于缺乏规范定义和处理技术导致癌症治疗后相关的淋巴水肿的精确发生率难以确定。
Lack of standardized definitions and measurement techniques for the disorder make an accurate incidence rate of cancer-treatment-related lymphedema difficult to determine, say the authors.
认为超重导致癌有较高的发生危险，尽管原因尚未完全清楚。
Being overweight is considered to lead to a higher risk of cancer, although the reasons are not fully understood.
过度肥胖而导致癌症风险提高这一事实和性别无关，而且这一现象在全球各地持续发生，包括北美，欧洲，亚洲，中东等地。 。
Thee cancer risks associated with excess weight were similar for men and women and were consistent across geographic regions -- North America, Europe, Asia and the Middle East, said the researchers.
肺癌发生的原因有很多种，有趣也很有挑战性，它的发生与外界致癌有关。
Lung cancer occurred for a variety of reasons, is also challenging interesting, the occurrence of cancer-related with the outside world.
科学家们发现超过100种一旦发生突变就可导致癌症的新基因。
Scientists have found more than 100 new genes that can cause cancer if they become mutated.
于是他们绘出了这些基因最终导致癌性肿瘤的路径，并且检查发生在特定组织的基因是否应用相同或不同的癌通路。
Then they mapped out how these genes ultimately lead to cancerous tumors and checked whether the genes occurring in specific tissues used the same or different cancer pathways.
科学家相信一些致癌物质、细胞内DNA分子意外地重新排列和 过滤性病毒感染等，都会触发癌症的发生。
Scientists believe that certain carcinogens, accidental rearrangement of DNA molecules in a cell, and virus infection can all be factors that trigger the action of cancers.
亚硝基脲的抗癌与致癌机理是非常接近的，都能够使DNA碱基发生烷化，进一步形成DNA股间交联。
The anticancer mechanism of nitrosoureas is very similar to the carcinogenic mechanism, both of them can alkylate DNA bases and form DNA cross-linking further.
异常的超变和异常的致癌基因BCL-6与淋巴瘤的发生具有相关性。
Aberrant somatic hypermutation and deregulation of the oncogene BCL-6 is associated with lymphomagenesis.
他们给第三组雄性小鼠雌激素，然后给与致癌剂，在这种情况下，肝癌的发生率与正常雌性小鼠相同。
The researchers also treated a third group of male mice with estrogen and then gave them the cancer-causing agent. In this case, rates of liver cancer remained the same as in normal female mice.
但这种措施是危险的，因为移植的干细胞经常是无序生长，而这种生长方式通常能导致癌症发生。
These interventions are risky. Transplanted cells often develop in an uncontrolled manner, which frequently leads to cancer.
背景：脂肪酸合成酶(FASN)过表达参与了前列腺癌的发生。我们直接研究FASN的致癌潜能。
Background: Overexpression of the fatty acid synthase (FASN) gene has been implicated in prostate carcinogenesis. We sought to directly assess the oncogenic potential of FASN.
干细胞本身需要接受严格的调控，调控的紊乱可能导致癌症，衰老或退行性疾病的发生。
Their dysfunction is believed to be intimately associated with various types of diseases such as cancer, degenerative diseases, and ageing, but the underlying mechanisms are poorly understood.
RAS突变或单独的scribbble突变均不能导致癌症发生。
Neither a mutated RAS nor the defective scribble alone can cause cancer.
确定这些潜在导致癌症发生的新基因，对研究正常细胞转化成为癌细胞的新途径来说至关重要。
The identification of these new potential cancer-causing genes is critical to uncovering novel pathways that drive the conversion of a normal cell to a cancerous one.
DNA损伤反应机制的任何功能缺陷将会引起基因组的不稳定性，从而导致癌症的发生。
Defects in DNA damage response can cause genome instability, which induces many human cancers.
研究表明睾丸素可能为一种抑癌基因，且当睾丸素基因表达降低或缺失时，致癌物诱导的胃癌发生率更高。
Our findings suggest that testin may represent a candidate tumor suppressor gene. When testin expression is degrade or deleted, the carcinogen-induced carcinoma incidence will be higher.
研究表明睾丸素可能为一种抑癌基因，且当睾丸素基因表达降低或缺失时，致癌物诱导的胃癌发生率更高。
Our findings suggest that testin may represent a candidate tumor suppressor gene. When testin expression is degrade or deleted, the carcinogen-induced carcinoma incidence will be higher.
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