目的探讨混合脐血移植重建造血和免疫功能的特点及规律。
Objective to evaluate characteristics of hematopoietic and immunologic reconstitution in mixed cord blood transplantation.
近年，脐血移植已广泛地用于治疗儿童白血病和恶性肿瘤等。
Till now cord blood transplantion has been widely used in treating leukemia and malignant tumor in children.
结果脐血移植后治疗组的血小板功能指标与对照组对比，有统计学差异。
Results The patients in experimental group showed significant improvement in platelet function than control group.
目的动态观察分析两份HLA不全相合异基因混合脐血移植后的植入状态。
Objective To observe and analyse the dynamic changes of engraftment status after transplantation of mixed umbilical cord blood from two units HLA one locus mismatched.
双份脐血移植（来自于两个不同的供者）10年钱在明尼苏达大学率先采用。
The practice of using two UCB units (from two different individuals) was pioneered at the University of Minnesota approximately 10 years ago.
结论CD34+CXCR4 +输入量与非亲缘脐血移植后的造血重建有关。
Conclusion The number of CD34+CXCR4+ cells reinfused is involved in hematologic reconstitution after unrelated umbilical cord blood transplantation.
目的：建立小鼠半相合脐血移植模型，探讨多位点不相合脐血移植后造血及免疫重建特性。
Purpose: to establish a murine model of haploidentical umbilical cord blood transplantation and evaluate the characteristic of hematopoietic and immunological reconstitution.
脐血移植有核细胞重建时间与输入的有核细胞数以及疾病类型相关，同HLA相合程度不相关。
The time of nuclear cell reconstitution after cord blood transplantation was statistically related with nucleated cells and the type of disease, not related with HLA matching.
脐血移植在临床上的应用，主要依赖于对脐血造血细胞的基础研究工作，包括脐血的生物学活性、采集、保存和输注等。
The clinical application of cord blood transplantation mainly depends on base study of hematopoietic cell, including biological activity, collection, retention and infusion of cord blood, and so on.
通过采用双份脐血，几乎所有的患者都可以寻找到移植所需的干细胞来源。
By using two UCB units, nearly all patients can now use this stem cell source for transplantation.
无论采用来自于外周血、骨髓或者脐血的干细胞进行移植，疾病的复发率都类似。
The relapse or disease recurrence rates are similar regardless of whether the stem cells used for transplantation are from bone marrow, peripheral blood, or umbilical cord blood.
目的：观察脐血干细胞移植对帕金森病(PD)大鼠神经功能恢复的影响。
Aim: To explore the effect of human umbilical cord stem cell transplantation on neurological function recovery of PD rats.
我们正在规划和筹集资金为这个网络做平行临床试验的脐血单个核细胞移植和锂移植治疗慢性脊髓损伤。
We are planning and raising money for this network to do parallel clinical trials of cord blood mononuclear cell transplants and lithium transplants in chronic spinal cord injury.
目的建立无关供者脐血干细胞库，用于治疗骨髓衰竭、恶性及非恶性血液病、某些遗传病、重型免疫缺陷等疾病的干细胞移植。
Objective To establish unrelated cord blood stem cell bank for providing potential grafts for stem cell transplantation in the treatment of some malignant and nonmalignant disorders.
结论脐血间质干细胞移植治疗可以显著改善ALS患者的神经系统功能。
Conclusion: the transplantation of umbilical cord blood MSCs on ALS patients can improve their nervous system function significantly.
目的：观察人脐血单个核细胞移植入大鼠脊髓损伤部位后的分化、迁移情况和损伤后功能的修复。
Aim: To observe the differentiation, immigration, and improvement of behavior after infusion human cord blood mononuclear cells (HCMNCs) in rat spinal cord injury model.
近年来，脐血造血干细胞移植已广泛用于治疗儿童白血病、先天性免疫缺陷病、遗传性代谢病等方面。
Till now cord blood transplantation has been widely used in treating children leukemia, inborn immune deficiency, heritage metabolic disease and so on.
Verneris和他的同事比较了分别采用一份和两份脐血进行移植的结果。
Verneris and his colleagues compared the outcomes of patients who were transplanted with one verses two UCB units.
目的：探讨脐血造血细胞体外扩增及移植的最佳时机。
Objective: To explore the optimal time for in vitro expansion and transplantation of umbilical cord blood hemopoietic cells.
使用双份脐血混合移植治疗白血病获得成功，激起人们对其相互作用机制的研究。
The successful treatment for leukemia with double units umbilical cord blood transplantation (UCBT) aroused the research on the mechanism of interaction between the two units UCB.
结论 脐带间充质干细胞与脐血CD34+细胞共移植可促进造血干细胞的植入，缩短CD34+细胞移植后造血恢复时间。
Conclusion The co-transplantation of MSC cells and CD34+ cells can promote hematopoetic stem cell transplantation and hematopoetic recovery in vivo.
结论 脐带间充质干细胞与脐血CD34+细胞共移植可促进造血干细胞的植入，缩短CD34+细胞移植后造血恢复时间。
Conclusion The co-transplantation of MSC cells and CD34+ cells can promote hematopoetic stem cell transplantation and hematopoetic recovery in vivo.
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